Gender differences in adolescent depression: Do symptoms differ for boys and girls?

Bennett, David S.; Ambrosini, Paul J.; Kudes, Diana; Metz, Claudia; Rabinovich, Harris

doi:10.1016/j.jad.2005.05.020

Cited by 152 publications

(114 citation statements)

References 46 publications

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“…Furthermore, a higher risk was observed in girls with a BMI of 18 kg/m 2 or more. This was consistent with the finding by Bennett et al that depressed girls had more body image dissatisfaction [4]. Psychosomatic disorders are commonly reported among subjects with advanced pubertal status [34].…”

Section: Discussionsupporting

confidence: 92%

“…A high prevalence of fatigue was also observed in other studies [35]. Sleep problems and chronic fatigue favor depression [4,34]. In addition, they may lead to difficulty working, which is also associated with depression [4].…”

Section: Discussionsupporting

confidence: 71%

“…Sleep problems and chronic fatigue favor depression [4,34]. In addition, they may lead to difficulty working, which is also associated with depression [4]. These findings underline the importance of investigating the causes of frequent tiredness in adolescents.…”

Section: Discussionmentioning

confidence: 87%

“…A poor body image may predispose people to depressive disorders [4] and result in adolescents becoming overweight [25]. It would therefore be interesting to examine the relationship between body mass index and long-term use of psychotropic drugs.…”

Section: Introductionmentioning

confidence: 99%

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Do male and female adolescents differ in the effect of individual and family characteristics on their use of psychotropic drugs?

et al. 2006

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 87%

Section: Introductionmentioning

confidence: 99%

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Do male and female adolescents differ in the effect of individual and family characteristics on their use of psychotropic drugs?

et al. 2006

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“…The average lifetime prevalence found was 6.7% (95% CI = 4.2-10.1) for major depressive disorder [3.8% (95% CI = 2.4-5.8) for men and 7.5% (95% CI = 4.5-11.3) for women] [37]. Similarly, women are about twice as likely as men to be diagnosed and treated for major depressive disorder in the United States [38]. Approximately 20-25% of women and 12% of men will experience a serious depression at least once in their lifetimes.…”

Section: Prevalence Of Depressionmentioning

confidence: 99%

Molecular epidemiology of major depressive disorder

Kiyohara

Yoshimasu

2009

Environ Health Prev Med

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Major depressive disorder causes significant morbidity, affecting people's ability to work, function in relationships, and engage in social activities. Moreover, major depressive disorder increases the risk of suicidal ideation, attempted suicide and death by completed suicide. There is evidence that chronic stress can cause major depressive disorder. As for genetic factors, only minor susceptibility genes have been reliably identified. The serotonin system provides a logical source of susceptibility genes for depression, because this system is the target of selective serotonin reuptake-inhibitor drugs that are effective in treating depression. The 5-hydroxytryptamine (serotonin) transporter (5-HTT) has received particular attention because it is involved in the reuptake of serotonin at brain synapses. One common polymorphic variant of the 5-HTT-linked polymorphic region (5-HTTLPR), which affects the promoter of the 5-HTT gene, causes reduced uptake of the neurotransmitter serotonin into the presynaptic cells in the brain. The authors discussed the relationship between genetic polymorphisms and major depressive disorder, with special emphasis on the 5-HTTTLPR polymorphism. As the 5-HTTLPR polymorphism was significantly associated with an increased risk of major depressive disorder, the 5-HTT gene may be a candidate for a major depressive disorder susceptibility gene. As major depressive disorder is a multifactorial disease, an improved understanding of the interplay of environmental and genetic polymorphisms at multiple loci may help identify individuals who are at increased risk for major depressive disorder. Hopefully, in the future we will be able to screen for major depressive disorder susceptibility by using specific biomarkers.

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Childhood Mood Disorders: Major Depressive Disorder, Bipolar Disorder, and Disruptive Mood Dysregulation Disorder

Hulvershorn

Leibenluft

2015

Psychiatry

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Gender differences in adolescent depression: Do symptoms differ for boys and girls?

Cited by 152 publications

References 46 publications

Do male and female adolescents differ in the effect of individual and family characteristics on their use of psychotropic drugs?

Do male and female adolescents differ in the effect of individual and family characteristics on their use of psychotropic drugs?

Molecular epidemiology of major depressive disorder

Childhood Mood Disorders: Major Depressive Disorder, Bipolar Disorder, and Disruptive Mood Dysregulation Disorder

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