Childhood Mood Disorders: Major Depressive Disorder, Bipolar Disorder, and Disruptive Mood Dysregulation Disorder

Hulvershorn, Leslie A.; Leibenluft, Ellen

doi:10.1002/9781118753378.ch52

Cited by 2 publications

(2 citation statements)

References 278 publications

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“…It plays a crucial role in daily functioning, influencing how individuals navigate social interactions, cope with stress, and make decisions. Dysregulation of emotions is a hallmark of numerous psychiatric conditions, including depression, anxiety, and borderline personality disorder, leading to significant impairment in quality of life (Grant et al, 2023;Petruso et al, 2023). Understanding the neural mechanisms underlying emotional regulation is therefore of paramount importance, as it holds the potential to uncover the root causes of these disorders and pave the way for novel therapeutic approaches (Barroso et al, 2021;Hussain et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Unraveling emotional regulation through multimodal neuroimaging techniques

Nilawati,

Amri,

Hasanah

et al. 2024

BrainBridge

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Neuroimaging techniques have significantly advanced our understanding of emotional regulation by elucidating the neural mechanisms involved. This review synthesizes findings across multiple modalities—functional Magnetic Resonance Imaging (fMRI), Electroencephalography (EEG), Magnetoencephalography (MEG), Positron Emission Tomography (PET), and Magnetic Resonance Spectroscopy (MRS)—to highlight key insights into emotional processing. The prefrontal cortex (PFC), amygdala, hippocampus, and insula emerge as critical brain regions in regulating emotions. fMRI studies demonstrate increased PFC activity and decreased amygdala responses during effective emotion regulation, indicating top-down control mechanisms. EEG and MEG provide insights into the temporal dynamics of emotional responses, capturing rapid changes in neural activity during emotional tasks. PET and MRS studies reveal the neurochemical basis of emotional regulation, emphasizing the roles of neurotransmitters like serotonin and dopamine. Integration of multimodal approaches, such as fMRI-EEG and fMRI-PET, enhances our understanding by combining spatial, temporal, and neurochemical specificity. Challenges include methodological limitations and the need for diverse participant samples to improve generalizability. Future research should focus on improving spatial and temporal resolution, adopting longitudinal and ecologically valid designs, and fostering interdisciplinary collaborations. These advancements hold promise for developing personalized interventions and treatments for emotional disorders by leveraging neuroimaging biomarkers and understanding the neural underpinnings of emotional regulation.

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Section: Introductionmentioning

confidence: 99%

Unraveling emotional regulation through multimodal neuroimaging techniques

Nilawati,

Amri,

Hasanah

et al. 2024

BrainBridge

View full text Add to dashboard Cite

show abstract

“…According to a comprehensive study, depression symptoms that begin at about 13 increase markedly during adolescence (Hankin et al, 1998). Research also suggests an abrupt increase in female depression during adolescence stems from increased estrogen levels (Hulvershorn & Leibenluft, 2015). A recent extensive study has shown that delays in developmental milestones are significantly correlated with developing depression and anxiety symptoms in adolescence (North et al, 2013).…”

Section: Introduction Depressionmentioning

confidence: 99%

The Disease of Our Time “Depression”: The Causes, Treatments and Influences on Children and Adolescents

KARTOL

2023

Celal Bayar Üniversitesi Sosyal Bilimler Dergisi

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As a common research agenda, depression is a mental disorder that affects all age groups and has serious negative impacts on the individual's life. Depressed children tend to seem compliant, quiet, and calm, so childhood depression can only be recognized and treated when they show certain behaviors such as school absenteeism or tantrum. Depressed children and adolescents cannot think clearly, so they cannot make healthy decisions in their family and school life and peer relationships, negatively affecting their academic and social life. In this respect, it is critical for children and adolescents prone to depression and less coping skills to seek help for their mental health and social well-being. This research aimed to raise awareness on this issue and to provide a resource to field experts and families by breaking down the prejudices that depression is only seen in adults. Therefore, this research would contribute to the relevant literature.

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Childhood Mood Disorders: Major Depressive Disorder, Bipolar Disorder, and Disruptive Mood Dysregulation Disorder

Cited by 2 publications

References 278 publications

Unraveling emotional regulation through multimodal neuroimaging techniques

Unraveling emotional regulation through multimodal neuroimaging techniques

The Disease of Our Time “Depression”: The Causes, Treatments and Influences on Children and Adolescents

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