Gender Dependent Differences in Composition, Antioxidant and Antimicrobial Activities of Wild and Cultivated <i>Laurus nobilis</i> L. Leaf and Flower Essential Oils from Aegean Region of Turkey

Demirbolat, İlker; Karik, Ünal; Erçin, Esin; Kartal, Murat

doi:10.1080/0972060x.2020.1843548

Cited by 8 publications

(7 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, the major components of LNEO from Laurus nobilis L. were chosen as potential ligands. As stated in the introduction, laurel leaf and flower essential oils contain 1,8-cineol, α-terpinyl acetate and methyleugenol as their main components [ 8 ]. In addition, the leaf essential oil contains at least 48% 1,8 cineole and 70% α-terpinyl acetate [ 9 ].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Laurus nobilis L. Essential Oil-Loaded PLGA as a Nanoformulation Candidate for Cancer Treatment

et al. 2022

Self Cite

View full text Add to dashboard Cite

The aim of this study was to obtain essential oil (LNEO) from the Laurus nobilis L. plant, and to prepare LNEO-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) as an approach in cancer treatment. The components of the obtained LNEO were analyzed using GC-MS. The LNEO-NPs were synthesized by the single-emulsion method. The LNEO-NPs were characterized using UV-Vis spectrometry, Dynamic Light Scattering (DLS), Scanning Electron Microscopy (SEM), and a DNA binding assay, which was performed via the UV-Vis titration method. According to the results, the LNEO-NPs had a 211.4 ± 4.031 nm average particle size, 0.068 ± 0.016 PdI, and −7.87 ± 1.15 mV zeta potential. The encapsulation efficiency and loading capacity were calculated as 59.25% and 25.65%, respectively, and the in vitro drug release study showed an LNEO release of 93.97 ± 3.78% over the 72 h period. Moreover, the LNEO was intercalatively bound to CT-DNA. In addition, the mechanism of action of LNEO on a dual PI3K/mTOR inhibitor was predicted, and its antiproliferative activity and mechanism were determined using molecular docking analysis. It was concluded that LNEO-loaded PLGA NPs may be used for cancer treatment as a novel phytotherapeutic agent-based controlled-release system.

show abstract

Section: Methodsmentioning

confidence: 99%

“…Laurel essential oil is usually obtained via hydrodistillation or steam distillation. Bay leaf and flower essential oils contain 1,8-cineol, α-terpinyl acetate and methyleugenol as their main components [ 7 , 8 ]. Turkish Pharmacopoeia includes bay leaf and bay leaf essential oil as national monographs.…”

Section: Introductionmentioning

confidence: 99%

Laurus nobilis L. Essential Oil-Loaded PLGA as a Nanoformulation Candidate for Cancer Treatment

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…While eugenol is included in the EU list of permitted flavorings [ 52 ], methyleugenol, which is biosynthetically related [ 56 , 57 ] and usually present at higher levels to eugenol, has been reported as toxic, thus restricting its direct application to the food and cosmetics industry [ 58 ]. Table 4 incorporates data for the eugenol and methyleugenol concentrations of bay laurel EOs from different Mediterranean countries, which show a considerable natural variability [ 13 , 15 , 18 , 22 , 26 , 27 , 28 , 51 , 53 , 57 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , …”

Section: Assessment Of the Preservative Propertiesmentioning

confidence: 99%

“…The protocols reported so far for the evaluation of its antioxidant activity present some similarities, but also differences regarding the reaction environment, concentrations of EOs and reagents, time span for reaction monitoring, and expression of results. Table 6 presents a detailed list of the DPPH • conditions of applications to bay laurel EO that can prove useful in future efforts for harmonization and standardization purposes [ 55 , 77 , 89 , 103 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 ].…”

Section: Assessment Of the Preservative Propertiesmentioning

confidence: 99%

Bay Laurel (Laurus nobilis L.) Essential Oil as a Food Preservative Source: Chemistry, Quality Control, Activity Assessment, and Applications to Olive Industry Products

Ordoudi

Papapostolou

Nenadis

et al. 2022

Foods

View full text Add to dashboard Cite

Essential oils (EOs) find application as flavoring agents in the food industry and are also desirable ingredients as they possess preservative properties. The Mediterranean diet involves the use of a lot of herbs and spices and their products (infusions, EOs) as condiments and for the preservation of foods. Application of EOs has the advantage of homogeneous dispersion in comparison with dry leaf use in small pieces or powder. Among them, Laurus nobilis (bay laurel) L. EO is an interesting source of volatiles, such as 1,8-cineole and eugenol, which are known for their preservative properties. Its flavor suits cooked red meat, poultry, and fish, as well as vegetarian dishes, according to Mediterranean recipes. The review is focused on its chemistry, quality control aspects, and recent trends in methods of analysis and activity assessment with a focus on potential antioxidant activity and applications to olive industry products. Findings indicate that this EO is not extensively studied in comparison with those from other Mediterranean plants, such as oregano EO. More work is needed to establish authenticity and activity methods, whereas the interest for using it for the preparation of flavored olive oil or for the aromatization and preservation of table oils must be further encouraged.

show abstract

“…In addition, VOs can be affected by endogenous factors such as developmental stages [ 17 ], genetic variability [ 18 , 19 ], and variety [ 20 ]. Moreover, plant sex has been reported to affect the chemical composition of the VOs either quantitively or qualitatively in many plants, such as Laurus nobilis L. [ 21 ] and Juniperus communis L. [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Volatile Oils Discrepancy between Male and Female Ochradenus arabicus and Their Allelopathic Activity on Dactyloctenium aegyptium

Abd‐ElGawad

Assaeed

Gendy

et al. 2022

Plants

View full text Add to dashboard Cite

Volatile oils (VOs) composition of plants is affected by several exogenous and endogenous factors. Male and female plants of the dioecious species exhibit variation in the bioactive constituents’ allocation. The chemical variation in the VOs between male and female plants is not well studied. In the present study, the chemical characterization of the VOs extracted from aerial parts of male and female ecospecies of Ochradenus arabicus was documented. Additionally, the extracted VOs were tested for their allelopathic activity against the weed Dactyloctenium aegyptium. Via GC-MS analysis, a total of 53 compounds were identified in both male and female plants. Among them, 49 compounds were identified from male plants, and 47 compounds were characterized in female plants. Isothiocyanates (47.50% in male and 84.32% in female) and terpenes (48.05% in male and 13.22% in female) were the main components of VOs, in addition to traces of carotenoid-derived compounds and hydrocarbons. The major identified compounds of male and female plants are m-tolyl isothiocyanate, benzyl isothiocyanate, butyl isothiocyanate, isobutyl isothiocyanate, carvone, and α-bisabolol, where they showed variation in the concentration between male and female plants. The O. arabicus VOs of the male plants attained IC50 values of 51.1, 58.1, and 41.9 μL L−1 for the seed germination, seedling shoot growth, and seedling root growth of the weed (D. aegyptium), respectively, while the females showed IC50 values of 56.7, 63.9, and 40.7 μL L−1, respectively. The present data revealed that VOs composition and bioactivity varied significantly with respect to the plant gender, either qualitatively or quantitatively.

show abstract

Gender Dependent Differences in Composition, Antioxidant and Antimicrobial Activities of Wild and Cultivated Laurus nobilis L. Leaf and Flower Essential Oils from Aegean Region of Turkey

Cited by 8 publications

References 38 publications

Laurus nobilis L. Essential Oil-Loaded PLGA as a Nanoformulation Candidate for Cancer Treatment

Laurus nobilis L. Essential Oil-Loaded PLGA as a Nanoformulation Candidate for Cancer Treatment

Bay Laurel (Laurus nobilis L.) Essential Oil as a Food Preservative Source: Chemistry, Quality Control, Activity Assessment, and Applications to Olive Industry Products

Volatile Oils Discrepancy between Male and Female Ochradenus arabicus and Their Allelopathic Activity on Dactyloctenium aegyptium

Contact Info

Product

Resources

About