Gels from small molecules in organic solvents: structural features of a family of steroid and anthryl-based organogelators

Abstract

Luminescent organogels formed by the small molecules cholesteryl 4-(2anthryloxy) butanoate (CAB) and 2,3-bis-n-decyloxyanthracene (DDOA) in decane and alcohol solvents have been studied by scattering techniques. The results are compared with previous studies of hydrocarbon-based gels of an androstanol derivative (STNH) analogue. Rheology experiments confirm that the materials, obtained through a sharp transition from a solution to a soft solid, have all of the characteristics of gels. For instance, the thermoreversible DDOA-octan-1-01 gel exhibits a yield stress (a* x 550 Pa at C = 1 wt.%), and its elasticity (G' x lo4 Pa) suggests the existence of numerous structural results have been confirmed by electron microscopy measurements. Structural correlations derived from studies of this family of gelators may bear upon the gelation process.

Fibrils of γ‐Oryzanol + β‐Sitosterol in Edible Oil Organogels

“…The systems are quite transparent up to high concentrations, and the components do not contain any of the saturated fatty acids that are responsible for crystallisation in most other systems. In fact, their chemical characteristics correspond much more with those of a number of cholesterol-derived systems investigated extensively by other groups in non-triglyceride solvents [23][24][25][26][27]. Those systems are known to form thin fibrils.…”

Oleogel: A promising base for transdermal formulations

“…Some pharmaceutical excipients were also identified as organogelators, namely sorbitan esters [6] and gelators with the cholesterol moiety. [7] Depending on the mechanism of the formation of the three dimensional skeleton, which help in immobilizing the non-polar phase, the oleogels are further categorized as fluidfilled structure and solid fiber-based oleogels. [5] With the advancement in the pharmaceutical, food, nutraceutical, and cosmetics industries, various oleogels based on non-biocompatible components are replaced by biocompatible one and have in use for human use.…”

Small-angle X-ray scattering from a dual-component organogel to exhibit a charge transfer interaction

“…Some of their scattering profiles are beautifully fitted by the theoretical calculation [11,31,33,34]. Therefore, the scattering nature of their organogels is similar to that of threadlike (or rodlike) micelles, although the organogel fibers are more rigid (with a greater persistence length) than the threadlike micelles.…”

“…Terech et al [11,[31][32][33][34][35] extensively studied SAXS and neutron small-angle scattering from the various organogels and showed that most of the scattering can be represented by particle scattering from randomly oriented cylinders with infinite length. Some of their scattering profiles are beautifully fitted by the theoretical calculation [11,31,33,34].…”