Gellan Nanohydrogels: Novel Nanodelivery Systems for Cutaneous Administration of Piroxicam

Musazzi, Umberto M.; Cencetti, Claudia; Franzè, Silvia; Zoratto, Nicole; Meo, Chiara Di; Procacci, Patrizia; Matricardi, Pietro

doi:10.1021/acs.molpharmaceut.7b00926

Cited by 25 publications

(15 citation statements)

References 38 publications

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“…X-beams photon therapy was evaluated with a focus on mice with CT26 growth. Reduced fitness and damage were found in cell lines treated by FeO nanoparticles [ 46 ].…”

Section: Nanomaterials For Skin Cancer Therapymentioning

confidence: 99%

Biomimetic Nanoscale Materials for Skin Cancer Therapy and Detection

Owida

2022

Journal of Skin Cancer

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Skin cancer has developed as one of the most common types of cancer in the world, with a significant impact on public health impact and the economy. Nanotechnology methods for cancer treatment are appealing since they allow for the effective transport of medicines and other biologically active substances to specific tissues while minimizing harmful consequences. It is one of the most significant fields of research for treating skin cancer. Various nanomaterials have been employed in skin cancer therapy. The current review will summarize numerous methods of treating and diagnosing skin cancer in the earliest stages. There are numerous skin cancer indicators available for the prompt diagnosis of this type of disease. Traditional approaches to skin cancer diagnosis are explored, as are their shortcomings. Electrochemical and optical biosensors for skin cancer diagnosis and management were also discussed. Finally, various difficulties concerning the cost and ease of use of innovative methods should be addressed and overcome.

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“…X-beams photon therapy was evaluated with a focus on mice with CT26 growth. Reduced fitness and damage were found in cell lines treated by FeO nanoparticles [ 46 ].…”

Section: Nanomaterials For Skin Cancer Therapymentioning

confidence: 99%

Biomimetic Nanoscale Materials for Skin Cancer Therapy and Detection

Owida

2022

Journal of Skin Cancer

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“…It was used in ocular delivery systems (Paolicelli et al, ; J. Sun & Zhou, ), cutaneous delivery systems (Musazzi et al, ), and for antibiotic delivery during wound healing (Shukla & Shukla, ). Additionally, oxygen‐producing biomaterials were developed based on gellan gum (Newland, Baeger, Eigel, Newland, & Werner, ).…”

Section: Polysaccharidesmentioning

confidence: 99%

Carbohydrate‐based nanomaterials for biomedical applications

Gim

Zhu

Seeberger

et al. 2019

WIREs Nanomed Nanobiotechnol

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Carbohydrates are abundant biomolecules, with a strong tendency to form supramolecular networks. A host of carbohydrate-based nanomaterials have been exploited for biomedical applications. These structures are based on simple monoor disaccharides, as well as on complex, polymeric systems. Chemical modifications serve to tune the shapes and properties of these materials. In particular, carbohydrate-based nanoparticles and nanogels were used for drug delivery, imaging, and tissue engineering applications. Due to the reversible nature of the assembly, often based on a combination of hydrogen bonding and hydrophobic interactions, carbohydrate-based materials are valuable substrates for the creations of responsive systems. Herein, we review the current research on carbohydratebased nanomaterials, with a particular focus on carbohydrate assembly. We will discuss how these systems are formed and how their properties are tuned. Particular emphasis will be placed on the use of carbohydrates for biomedical applications.

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“…Musazzi and collaborators studied the feasibility of a delivery system based on gellan nanohydrogels to be used for the cutaneous administration of piroxicam . The researchers synthesized the nanogels by conjugating gellan with cholesterol or riboflavin.…”

Section: Gellan Gummentioning

confidence: 99%

Advancement in the Biomedical Applications of the (Nano)gel Structures Based on Particular Polysaccharides

Chiriac¹,

Ghilan²,

Neamţu³

et al. 2019

Macromolecular Bioscience

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The ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/mabi.201900187. Nanogels (Nano)gels from macromolecular compounds-natural, synthetic, or a combination thereof, suitable crosslinkers-and conferred characteristicssuch as degradability, size, charge, amphiphilicity, responsiveness, and softness-are capable of responding to the challenges imposed by bioengineering applications. Polysaccharide-based gels have received particular attention in this field. This review addresses recent advancement in the use of (nano)gel structures prepared only from compounds based on gellan gum, heparin, chondroitin sulfate, carrageenan, guar gum, galactose, or agarose, which represent an important part of the special class of natural polymers, the polysaccharides. Also, future trends are taken into discussion regarding the (nano)gels' use in biomedical applications such as biomimetics, biosensors, artificial muscles, and chemical separations in relation with their ability to be used as a vehicle for various biomolecules due to their physicochemical properties, biocompatibility, and biodegradability.

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Gellan Nanohydrogels: Novel Nanodelivery Systems for Cutaneous Administration of Piroxicam

Cited by 25 publications

References 38 publications

Biomimetic Nanoscale Materials for Skin Cancer Therapy and Detection

Biomimetic Nanoscale Materials for Skin Cancer Therapy and Detection

Carbohydrate‐based nanomaterials for biomedical applications

Advancement in the Biomedical Applications of the (Nano)gel Structures Based on Particular Polysaccharides

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