Gel immersion endoscopic mucosal resection with acetic acid spray for sessile serrated lesion extending close to the appendiceal orifice

Takada, Kazunori; Imai, Kenichiro

doi:10.1111/den.14343

Cited by 4 publications

(3 citation statements)

References 6 publications

(6 reference statements)

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“…In GIEMR, the gastrointestinal tract lumen is filled with a gel; this allows better visibility compared with that provided by water immersion 2,3 . In this case, the floating effect of gel immersion allowed a clear view of the stalk, 4 leading to smooth and accurate snaring.…”

Section: Brief Explanationmentioning

confidence: 99%

Gel immersion endoscopic mucosal resection for intussuscepted small bowel polyp in a patient with Peutz–Jeghers syndrome

Daiki

Takada

2023

Digestive Endoscopy

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Section: Brief Explanationmentioning

confidence: 99%

Gel immersion endoscopic mucosal resection for intussuscepted small bowel polyp in a patient with Peutz–Jeghers syndrome

Daiki

Takada

2023

Digestive Endoscopy

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“…The usefulness of GIEMR has been reported for endoscopic resection in the stomach, duodenum, and colon [ 19 , 20 , 21 ]. However, evidence on the use of GIEMR for colorectal polyps is limited to a few case reports [ 22 ]. As discussed above, piecemeal or incomplete resection with CEMR is problematic for NPCRNs.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Gel Immersion Endoscopic Mucosal Resection for Non-Pedunculated Colorectal Polyps

Ashizawa

Imai

Ito

et al. 2023

Life

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Underwater endoscopic mucosal resection (UEMR) has become a popular endoscopic resection method for large colorectal neoplasms. However, visualization can be poor during UEMR due to the presence of intestinal fluid. Gel immersion endoscopic mucosal resection (GIEMR), using a specially developed gel (Viscoclear®, Otsuka Pharmaceutical Factory, Tokushima, Japan), can improve the visual field. However, reports of GIEMR for colorectal polyps are limited. Herein, we evaluated the short-term outcomes of GIEMR for non-pedunculated colorectal neoplasms (NPCRN). This single-center, retrospective, and observational study includes 25 lesions in 20 patients with NPCRN who underwent GIEMR between January and October 2022. The short-term outcomes and adverse events were evaluated. The lesion locations were as follows: right colon, 18 lesions; left colon, 7 lesions; and rectum, none. The median tumor diameter was 15 (IQR, 10–18) mm. Histological classification was as follows: sessile serrated lesion, 9 cases; adenoma, 12 cases; and intramucosal adenocarcinoma, 4 cases. The overall en bloc resection rates and R0 resection rates were 80% (20/25) and 72% (18/25). For NPCRN in 10–19 mm, the en bloc resection rate was 75% (12/16), with an R0 resection rate of 69% (11/16). No post-polypectomy bleeding, perforation, or post-coagulation syndrome were observed. The findings of our study provide preliminary evidence of the efficacy and safety of GIEMR for NPCRN. Therefore, GIEMR may be a promising novel endoscopic resection method for NPCRN.

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“…5), which was confirmed by biopsies. The efficacy of gel immersion EMR has been reported mainly in the duodenum and colon [2][3][4]. This method has also been used for gastric cancer near the pyloric ring, where it is difficult to submerge in water and the workspace is narrow [5].…”

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Gel immersion endoscopic mucosal resection for a gastric neoplasm with a background of fundic gland polyposis

Kimura

Morita

et al. 2022

Endoscopy

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Gel immersion endoscopic mucosal resection with acetic acid spray for sessile serrated lesion extending close to the appendiceal orifice

Abstract: https://onlinelibrary.wiley.com/pages/journal/14431661/den14343-sup-0001-VidS1.htm a video of this article

Cited by 4 publications

References 6 publications

Gel immersion endoscopic mucosal resection for intussuscepted small bowel polyp in a patient with Peutz–Jeghers syndrome

Gel immersion endoscopic mucosal resection for intussuscepted small bowel polyp in a patient with Peutz–Jeghers syndrome

Efficacy and Safety of Gel Immersion Endoscopic Mucosal Resection for Non-Pedunculated Colorectal Polyps

Gel immersion endoscopic mucosal resection for a gastric neoplasm with a background of fundic gland polyposis

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