GC-MS Screening of Sungkai Leaves and Relation With Its Antioxidant Capacity

Abstract

Sungkai (Peronema canescens Jack) is a wild plant that grows in Kalimantan and Sumatera, Indonesia, and is used as traditional medicine. This study aimed to determine the components of chemical compounds in young leaves, half-old leaves, and old leaves of sungkai and their antioxidant activity. Gas Chromatography-Mass Spectrometry analyzed chemical compounds (GC-MS), and antioxidant activity was evaluated by 1,1-diphenyl-2-picrylhydrazil (DPPH). The analysis of chemical compounds showed that the chemical compounds were almost similar in young, half-old, and old leaves of sungkai with different intensities. Antioxidant activity showed the strong activity with IC50 of young leaves of sungkai is 26.389 mg/L, half-old leaves 29.874 mg/L and old leaves 30.9183 mg/L.

Extraction of Sungkai (Peronema cannescens Jack) leaves, Antioxidant Activity Test and Its Nanoemulsion Formulation

“…The leaves and roots of sungkai have also long been used as traditional medicine in the Dayak Tunjung tribe as a medicine for fever, diuretic and rheumatic pain, and the Lembak Empat tribe in Bengkulu still uses the young leaves of sungkai to maintain health, treat high fever and malaria [1]. Currently, sungkai research focuses on leaves as an extract which has potential as an antipyretic [2] anti-inflammatory [3,4], antioxidant [5][6][7][8], antibacterial [9][10][11], Antihyperuricemia [12], anticancer [13,14], and antidiabetic [15,16].…”