GC-MS and Antioxidant Capacity Analysis in Propanol Extract of Carthamus Tinctorious L

Indriati, Sri; Yusuf, Muhammad; Riskayanti, Riskayanti; Amaliah, Nur; Latief, Mahyati; Sjafruddin, Rahmiah; Attahmid, Nur Fitriani Usdyana

doi:10.31963/intek.v8i1.2801

Cited by 2 publications

(4 citation statements)

References 17 publications

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“…Tetracontane showed antibacterial against Staphylococcus aureus, Bacillus cereus, and Pseudomonas aeruginosa and antioxidant activity (Belkacemi et al, 2020). Therefore, Gollo et al (2020) and Indriati et al (2021) reported that extracts with tetracontane compounds indicated antioxidant activity. The antibacterial activity of flowers might be related to tetracontane in the extracts, as reported by Belkacemi et al (2020).…”

Section: Antimicrobial Activitymentioning

confidence: 98%

“…Tetracontane is one of the major compounds which was only detected in flower samples at a retention time of 31.26 minutes with a peak area of 11.41%. Tetracontane is a natural product with anti-inflammatory, analgesic (Arora & Meena, 2017), antibacterial and antioxidant (Belkacemi et al, 2020;Indriati et al, 2021). Stigmast-5-en-3-ol, (3.beta.,24S)-(CAS) Clionasterol is known to have antiinflammatory, antipyretic, anti-ulcer, and antiarthritis (Arora & Meena, 2017).…”

Section: Analysis Of Bioactive Compounds On N-hexane Extractsmentioning

confidence: 99%

“…The antibacterial activity might be due to some bioactive compounds, such as tetratetracontane and tetracontane. However, most bioactive compounds are known to have more roles as antioxidants (Amudha et al, 2018), anti-inflammatory, analgesic (Arora & Meena, 2017;Duraisamy & King, 2020), antioxidant (Indriati et al, 2021), immunostimulant, and chemopreventive (Sudha et al, 2013). It can be the basis for carrying out a potential screening process as bioactive prospectives from ramie plants.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

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Analysis of the Bioactive Compounds N-Hexane Extract of Ramie Leaves and Flowers (Boehmeria nivea) and Antibacterial Test Against Escherichia coli and Klebsiella pneumoniae

2022

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Ramie (Boehmeria nivea) is one of the Urticaceae family plants with various potential for pharmacological development. In this study, we analyzed the bioactive content of the n-hexane extract of B. nivea leaves and flowers, and the crude extract was tested for antibacterial activity. The metabolites in the leaves and flowers of ramie were analyzed using a Gas Chromatography-Mass Spectrometer (GC-MS). Antibacterial potential analysis was carried out by disc diffusion method using n-hexane extract of ramie leaves and flowers at concentrations of 20%, 40%, 60%, 80%, and 100% in inhibiting Escherichia coli and Klebsiella pneumoniae. Antibacterial potential was observed based on the average result of three observations of the diameter of the clear zone to determine the effectiveness of the extract. The results showed that the metabolome data of the n-hexane extract of ramie leaves were obtained as many as 40 compounds. Meanwhile, ramie flower metabolome analysis obtained 47 compounds, but one compound has not been identified. The crude n-hexane extract of B. nivea flower gave antibacterial activity at 80% and 100% concentrations against E. coli with an average clear zone of 9.15 ± 0.31 mm and 10.29 ± 0.28 mm. In contrast, the n-hexane extract of B .nivea leaves did not show any antibacterial activity. The results of confirmation of the dominant compound by GC-MS showed that the n-hexane extract consisted of tetratetracontane, tetracontane, Stigmast-5-en-3-ol,(3.beta.,24S)-(CAS)Clionasterol, methyl commate D, and 2,6,10,14,18,22-Tetracosahexsaene,2,6,10,15,19,23-hexamethyl-, (all-E). The n-hexane extract of B. nivea is recommended for other potential biological activities, such as anti-inflammatory, antioxidant, and analgesic.

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Section: Antimicrobial Activitymentioning

confidence: 98%

Section: Analysis Of Bioactive Compounds On N-hexane Extractsmentioning

confidence: 99%

Section: Antimicrobial Activitymentioning

confidence: 99%

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Analysis of the Bioactive Compounds N-Hexane Extract of Ramie Leaves and Flowers (Boehmeria nivea) and Antibacterial Test Against Escherichia coli and Klebsiella pneumoniae

2022

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“…Non-Steroidal, analgesics, anti-Inflammatory, antihypertensive, neuroprotective, antiviral,anticonvulsant, anti-oxidative 49 24…”

Section: Mome Inositolmentioning

confidence: 99%

Antimicrobial activity and GCMS Analysis of leaves Extracts of Butea Monosperma Lam Taub

Ambastha,

Patnaik,

Oraon

et al. 2023

Def. Life. Sc. Jl.

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Butea monosperma (Lam.) Taub is a well-known medicinal plant belonging to the family Fabaceae. More than hundreds of plants have been reported in the Ethno-botanical literature of India for theiranti-microbial activity as well as for treatment of many diseases and Butea monosperma (Lam.)Taub is one of them. The present investigation is focused on the anti-microbial activity of Butea monosperma leaves against both gram-positive (Bacillus subtilis, Enterococcus faecalis, Lactobacillus acidophilus, Staphylococcus aureus and Streptococcus mutans) and gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) as well as fungi (Candida albicans and Trichophyton rubrum). Both excerpts (ethanol and methanol) show positive responses against all the selected microorganisms. GC-MS analysis is done to find out important compound which is anti-microbial. A total of 38 compounds are identified in GC-MS analysis. Out of 38 compounds, 8 compounds are identified as antimicrobial in nature such as Dodecane, 2-HEXADECEN-1-OL, 3,7,11,15-TETRAMETHYL-, [R-[, Hexadecanoic acid, methyl ester, Phytol, Palmidrol, Squalene, Tetracosane, Vitamin E and Lup-20(29)-en-3-one which justify, this plant possess significant anti-microbial property. GC-MS analysis reveals that majorly, this plant leaves also possess 10 antioxidant compounds (Neophytadiene, 2-HEXADECEN-1-OL, 3,7,11,15-TETRAMETHYL-, [R-[, n-Hexadecanoic acid, Phytol, squalene, .alpha.-Tocospiro B, Tetracosane, .gamma.-Tocopherol, Ergost-5-en-3-ol, (3.beta.)- and STIGMASTA-5,22-DIEN-3-OL, (3.BETA.,22E)-,), 9 anti-cancerous compounds (Hexadecanoic acid, methyl ester, 9,12,15-OCTADECATRIENOIC ACID, METHYL ESTER, squalene, .gamma.-Tocopherol, Vitamin E, Ergost-5-en-3-ol, (3.beta.)-, STIGMASTA- 5,22-DIEN-3-OL, (3.BETA.,22E)-, .gamma.-Sitosterol and Lupeol),8 anti-inflammatory compounds (Neophytadiene,2-HEXADECEN-1-OL, 3,7,11,15-TETRAMETHYL-, [R-[, Hexadecanoic acid, methyl ester, n-Hexadecanoic acid, 9,12,15-OCTADECATRIENOIC ACID, METHYL ESTER, Phytol, Palmidrol, .alpha.-Tocospiro B and Lupeol), 3 cardioprotective compounds ( Neophytadiene, .alpha.-Tocospiro B and .gamma.-Tocopherol A) and 5 antidiabetic compounds (.alpha.-Tocospiro B, Vitamin E, STIGMASTA-5,22-DIEN-3-OL, (3.BETA.,22E)-, .gamma.-Sitosterol and Lup-20(29)-en-3-one).This investigation suggests that this plant leaf has not only anti-microbial potential but also possesses other important compounds to fight against many deadly diseases. Thus, this plant has immense potential to make an individual place in pharmacological industries, especially as antibiotics.

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GC-MS and Antioxidant Capacity Analysis in Propanol Extract of Carthamus Tinctorious L

Cited by 2 publications

References 17 publications

Analysis of the Bioactive Compounds N-Hexane Extract of Ramie Leaves and Flowers (Boehmeria nivea) and Antibacterial Test Against Escherichia coli and Klebsiella pneumoniae

Analysis of the Bioactive Compounds N-Hexane Extract of Ramie Leaves and Flowers (Boehmeria nivea) and Antibacterial Test Against Escherichia coli and Klebsiella pneumoniae

Antimicrobial activity and GCMS Analysis of leaves Extracts of Butea Monosperma Lam Taub

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