2008
DOI: 10.1038/ijo.2008.235
|View full text |Cite
|
Sign up to set email alerts
|

Gastrointestinal satiety signals

Abstract: Obesity constitutes a major global healthcare challenge. The morbidity, mortality, and socioeconomic costs of obesity are considerable. No currently available medical therapy delivers substantial, sustainable weight loss. The need to better understand the mechanisms of appetite regulation is therefore clear. Over the last 20 years, peptide hormones released from the gastrointestinal tract in response to nutritional stimuli have come to be recognized as important physiological regulators of appetite. Hormones s… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
18
0
2

Year Published

2010
2010
2016
2016

Publication Types

Select...
5
4
1

Relationship

0
10

Authors

Journals

citations
Cited by 46 publications
(24 citation statements)
references
References 38 publications
0
18
0
2
Order By: Relevance
“…Several mechanisms could have been responsible for these differences. Enhanced satiety and reduced hunger immediately after HENSD supplementation can be attributed to significantly higher plasma concentrations of PYY and CCK, which are known to elicit anorexigenic effects (Chaudhri, Field, & Bloom, 2008;Suzuki, Simpson, Minnion, Shillito, & Bloom, 2010) and to insulin, which plays a role in appetite regulation of lean individuals (A. Flint et al, 2007).…”
Section: Hensd Placebomentioning
confidence: 99%
“…Several mechanisms could have been responsible for these differences. Enhanced satiety and reduced hunger immediately after HENSD supplementation can be attributed to significantly higher plasma concentrations of PYY and CCK, which are known to elicit anorexigenic effects (Chaudhri, Field, & Bloom, 2008;Suzuki, Simpson, Minnion, Shillito, & Bloom, 2010) and to insulin, which plays a role in appetite regulation of lean individuals (A. Flint et al, 2007).…”
Section: Hensd Placebomentioning
confidence: 99%
“…On the other hand, another hypothesis relies on the idea that fermentation of SCFAs influences gut hormones and gastric motility (Brighenti et al 2006;Nilsson et al 2008). Also, other scientific data suggest that the decrease in food intake associated with prebiotics feeding in animals might be linked to the modulation of gastrointestinal peptides involved in the regulation of food intake (Druce et al 2004;Chaudhri et al 2008).…”
Section: Obesity and Diabetesmentioning
confidence: 99%
“…Gut hormones have a variety of physiological actions outside the intestine, and play a central role in linking food ingestion to peripheral nutrient disposal and appetite (3,4). Indeed, glucagon-like peptide-1 (GLP-1) analogs and inhibitors of GLP-1 degradation are now widely prescribed for the treatment of type 2 diabetes, offering additional beneficial effects on body weight compared with conventional insulin secretagogues (5,6).…”
mentioning
confidence: 99%