Gastroesophageal reflux disease in patients with various comorbidal pathology

Abstract

The aim of the workconduct a literature review to study the most important and complex aspects in the diagnosis and treatment of gastroesophageal reflux disease that are encountered in the practice of a family doctor. Results. Gastroesophageal reflux disease is becoming an increasingly important disease for the young and ablebodied population, which gives it not only a medical, but also an economic aspect. This is one of the most common pathologies in the practice of not only a therapist, family doctor and gastroenterologist, butdue to the presence of extraesophageal manifestationsin a wider range of medical specialties. Since gastroesophageal reflux disease has many "masks", this leads to delayed diagnosis and treatment. This disease does not have a "gold standard" in routine diagnostics, and the presence of its refractory forms leads to treatment failures and complications. With a comorbid course of gastroesophageal reflux disease, both diagnosis and treatment require an integrated approach. Conclusions. Gastroesophageal reflux disease remains one of the most common diseases in the practice of a family doctor. Despite the extensive study of this pathology, it continues to remain difficult in terms of diagnosis and treatment, which is associated with the presence of extraesophageal manifestations, comorbid and refractory course. This requires an additional study of pathogenetic mechanisms and the development of therapeutic and diagnostic measures on the basis of this