Gastroesophageal Reflux and Gastric Emptying

Section: Methodsmentioning

confidence: 99%

Clinical Presentation, Response to Therapy, and Outcome of Gastroparesis in Children

Rodriguez

Irani

Jiang

et al. 2012

“…There is conflicting data in the literature regarding correlation between gastric emptying and the severity of GER (10,20). Our previous study has also failed to show correlation between GE and GER on extended pH monitoring in infants (21).…”

Section: Resultsmentioning

confidence: 84%

Gastric Emptying Using Three Different Formulas in Infants with Gastroesophageal Reflux

Tolia,

Lin,

Kuhns

1992

SummaryThe role of delayed gastric emptying (GE) in the pathogenesis of gastroesophageal reflux (GER) in infants is controversial at present. GE has been shown to be altered by the composition and osmolality of the feedings. This prospective study was undertaken to assess the changes in the GE and the percentage of time GER was detected by scintigraphy using three different formulas on consecutive days in infants with GER. Twenty‐eight infants under 1 year of age diagnosed to have GER by extended intraesophageal pH monitoring (pH being <4.0 for >5% of the duration of the test), underwent scintigraphy on three consecutive days using the same volume per single feeding of a casein‐predominant, soy, or a wheyhydrolysate formula in a randomized order. The formulas were isocaloric. Gastric emptying and percentage of GER into the esophagus were estimated for 60 min following these feedings. Mean GER percent during the study was 20.39, 17.68, and 16.34 on casein‐predominant, soy, and whey‐hydrolysate formulas, respectively, and was not significantly different. Mean values of GE were 39.7%, 44.6%, and 48.5% on casein, soy, and whey formula, respectively. No significant difference in GE was also observed between casein‐predominant and soy formula. However, a significant difference was observed (p < 0.05) on GE between casein‐predominant and whey‐hydrolysate feedings. Our data suggest that formula selection may be important in the treatment of conditions associated with delayed gastric emptying.

“…Age was a significant factor among women, with shorter GET in postmenopausal than in premenopausal women (20,21). Similarly, in a scintigraphic study of 126 children suspected of having gastroesophageal reflux, a significantly shorter GET was found in children older than 2 years compared with those younger than 2 years (22). Other investigators reported similar GET of solids in children and adults but a slower emptying time of cream milk in children (23).…”

Section: Discussionmentioning

confidence: 91%

“…Despite the well-known deleterious effects of peritonitis on gastrointestinal motility (19), we had only 5 children with peritonitis due to perforated appendicitis, a sample size that is too small for valid statistical analysis. The role of sex, age, and weight in GET of food and liquid was assessed by others (20)(21)(22)(23)(24)(25). Men were shown to have a significantly faster GET of food and liquids than women.…”

Section: Discussionmentioning

confidence: 99%

Gastric Emptying Time of Oral Contrast Material in Children and Adolescents Undergoing Abdominal Computed Tomography

Berger-Achituv

Zissin²,

Shenkman³

et al. 2010