Gastric tuberculosis presenting as a large gastric ulcer

Elterefi, Alanood Eisameldin; Uwaydah, Ahmad Kanaan; Helal, Gamal Rashed; Hassan, Nidal M M

doi:10.1136/bcr-2021-248215

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…More than 80% of gastric tuberculosis is ulcerative, and some patients with gastric tuberculosis can even show giant gastric ulcers. [12] The gold standard for the diagnosis of gastric tuberculosis is to find the presence of a caseous epithelioid granuloma or acidophilus under the pathological examination of the biopsy tissue. For the treatment of gastric tuberculosis, antituberculosis therapy is generally used.…”

Section: Discussionmentioning

confidence: 99%

Primary gastric tuberculosis was misdiagnosed as submucosal mass: A rare case report and review of literature

Feng

Zhang

et al. 2023

Medicine

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Background: Tuberculosis of stomach is the rarest form of the tuberculosis family. It is not only lacks specificity in clinical symptoms, but also lacks specificity in auxiliary examination results such as upper gastrointestinal barium meal and gastroscopy. In addition, gastric tuberculosis can coexist with gastric ulcer or gastric cancer, which is difficult to confirm the diagnosis and easy to misdiagnose. Case summary: We report a patient who presented with gastric discomfort as the main symptom and was diagnosed with gastric submucosal mass at a local hospital several months ago. For further endoscopic treatment, the patient came to our hospital for hospitalization. Conclusion: We performed endoscopic ultrasonography and histopathological biopsy for the patient, and found that the “submucosal mass” was actually a gastric tuberculosis lesion. After confirming the diagnosis of gastric tuberculosis, we transferred the patient to a tuberculosis specialist hospital for antituberculosis treatment. Through a series of literature review, we rediscuss the diagnosis and differential diagnosis of gastric tuberculosis, aiming at improving the understanding of gastroenterologists to this disease, so as to timely diagnose and treat patients with gastric tuberculosis.

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Section: Discussionmentioning

confidence: 99%

Primary gastric tuberculosis was misdiagnosed as submucosal mass: A rare case report and review of literature

Feng

Zhang

et al. 2023

Medicine

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Infectious Gastric Diseases Other than Helicobacter

Jo,

Shin

2023

Korean J Gastroenterol

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In addition to Helicobacter pylori, the acute bacterial causes of infectious gastritis, include phlegmonous gastritis, gastric tuberculosis, and gastric syphilis. Bacterial gastritis often improves with appropriate broad-spectrum antibiotics, emphasizing the need for prompt diagnosis and treatment based on the clinical and endoscopic findings. Among viral gastritis, cytomegalovirus gastritis, primarily occurring in immunocompromised patients, necessitates antiviral intervention, while immunocompetent individuals typically achieve amelioration by administering proton pump inhibitors. In contrast, most gastric infections caused by the Epstein-Barr virus (EBV) are asymptomatic, but an EBV infection is a cause of stomach cancer. EBV-associated gastric cancer exhibits distinct clinical, pathological, genetic, and post-genetic mutation features, making it clinically significant. The colonization of Candida albicans in the stomach is uncommon, and typical antifungal treatment is unnecessary. Candida infections in gastric ulcers can be treated with anti-ulcer treatment alone. Lastly, anisakidosis in the stomach, which occurs when consuming raw seafood, can manifest in various clinical presentations and is typically treated through endoscopic removal of the nematode. This article aims to contribute to the rapid diagnosis and treatment of rare stomach infections beyond Helicobacter pylori in real clinical situations.

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Rare Bacterial Infection of the Stomach

Cho,

Kim,

Jang

et al. 2024

Korean J Helicobacter Up Gastrointest Res

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An acidic environment, gastric emptying, and abundant blood supply inhibit bacterial infection of the stomach. Helicobacter pylori can evade these defense mechanisms and is a well-known etiological contributor to chronic gastritis. Non-H. pylori bacterial infections such as acute phlegmonous gastritis, gastric syphilis, gastric tuberculosis, and gastric actinomycosis are uncommon and owing to their nonspecific findings, are diagnostically challenging in patients without a high index of clinical suspicion. Predisposition to bacterial infection is attributable to an increase in the prevalence of medical conditions and factors that precipitate immunosuppression, in addition to high rates of gastric mucosal injury associated with endoscopic procedures. Gastric bacterial infection negatively affects patients’ quality of life, increases the socioeconomic burden, and may occasionally be fatal. Therefore, physicians should be familiar with the endoscopic features and clinical manifestations of non-H. pylori bacterial infections of the stomach.

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Gastric tuberculosis presenting as a large gastric ulcer

Cited by 3 publications

References 16 publications

Primary gastric tuberculosis was misdiagnosed as submucosal mass: A rare case report and review of literature

Primary gastric tuberculosis was misdiagnosed as submucosal mass: A rare case report and review of literature

Infectious Gastric Diseases Other than Helicobacter

Rare Bacterial Infection of the Stomach

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