Gastric polyps: a 10-year analysis of 18,496 upper endoscopies

Abstract

Background/aims Gastric polyps (GPs) are usually asymptomatic lesions of the upper gastrointestinal tract observed in 1–3% of esophagogastroduodenoscopies (EGD). Most GPs are benign. The aim of this study was to precise the frequency of different types of gastric polyps in our population, and to analyze their possible association with other factors. Materials and methods A total of 18,496 consecutive patients undergoing EGD over a 10-year period (between 2007 and 2018) in a tertiary hospital were retrospectively reviewed. Eighty-six patients diagnosed with gastric polyps were analysed. Demographics, medical history of the patients, and indication for gastroscopy were collected. Morphological, histological characteristics of polyps, and therapeutic management data were also collected. Results GPs were found in 86 out of 18,496 (0.46%) reviewed EGD, corresponding to a total of 141 polyps. There were 64 female (74.4%) and 22 male patients (25.6%) with a sex ratio (M/F) of 0.34. The average age was 58.1 years. One hundred and forty one polyps were included, and histopathology was obtained on 127 GPs. The most common location was the fundus (59.6%) and 48.9% were smaller than 5 mm. The polyp was unique in 75.6% of cases. According to Paris classification, 80% of the polyps were sessile (Is). Hyperplastic polyps were the most common (55.9%), followed by sporadic fundic gland polyps observed in 23 patients (18.1%), 7 (5.5%) were adenomas and 4 (3.1%) were neuroendocrine tumors type 1. The following factors were associated with hyperplastic polyps: anemia (p = 0.022), single polyp (p = 0.025) and size ≥ 5 mm (p = 0.048). Comparing hyperplastic polyps’ biopsies to resected polyps, no difference was found in the evolutionary profile of the 2 groups. A size less than 10 mm (p = 0.013) was associated with fundic gland polyps. Sixty polyps (47.2%) were treated by cold forceps, 19 (15%) treated by a mucosal resection and 15 (11.8%) with diathermic snare. Five procedural bleeding incidents were observed (3.9%). Only the use of anticoagulant treatment was associated with a high bleeding risk (p = 0.005). The comparative histological study between specimens of biopsied GPs and endoscopic polypectomy led to an overall agreement of 95.3%. Conclusion In our study, the GPs frequency was 0.36%. Hyperplastic polyps and fundic gland are the most common in our country. The high frequency of Helicobacter pylori infection in our patients and in our area may explain the high frequency of HP.

The Prevalence and Risk Factors of Gastric Polyp in Endoscopy Unit at Prof. Dr. R.D. Kandou Hospital

“…15 The median age of patients with gastric polyp in our study was 57 years old, this finding was in line with study by Yacoub et al which found the mean age of 58.1 years old. 16 Study by Jeong et al in South Korea, also found that the median age of FGP patients was 54 years old and for hyperplastic polyp was 58 years old. 17 We found that older patients was significantly associated with more prevalent of gastric polyp, this finding is supported by Park et al 18 Therefore, older age may become risk factor of gastric polyp.…”

The association between duration of and indications for proton pump inhibitor use and risk of gastric polyps

“…Gastric polyps are common abnormal findings in up to 2-7% of upper gastrointestinal endoscopies, and fundic gland polyps (FGPs) and hyperplastic polyps are the main abnormalities identified, with broad variability worldwide [1][2][3][4][5]. Changes occur in gastric polyps over time, with the proportion of FGPs becoming predominant and hyperplastic and adenomatous polyps decreasing in number [6].…”

Gastric Polyps: Retrospective Analysis of a 10-Years Endoscopic Procedure

“…Most gastric polyps are benign (>85% of cases). The risk of malignancy or malignant transformation of gastric polyps depends on their histological structure (7). Due to the increased incidence of gastric neoplasia, encountering a polyp in the stomach during endoscopy causes concern in regard to malignant potential.…”