Gastric Metastasis of Merkel Cell Cancer — Uncommon Complication of a Rare Neoplasm

Anaemia due to gastric haemorrhage by a metastatic Merkel cell carcinoma

“…Merkel cell carcinoma rarely metastasises to the stomach. However, a few cases have been reported in the literature with an interesting recent study performed by Syal et al ., pointing out that up to 80% of patients with gastric metastasis of MCC presented with upper gastrointestinal bleeding consistent with the presented case [ 12 ]. Furthermore, they also noted that the mean time between upper gastrointestinal bleeding due to a metastatic MCC and death is about 4 months [ 12 ], slightly less than the 6-month survival observed in our patient.…”

Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis

“…[3][4][5][6][7][8][9][10][11][12][13][14][15] Mortality rates range from 1 week to 24 months with an average mortality rate of 67% at 4 months following diagnosis of gastric metastasis. [3][4][5][6][7][8][9][10][11][12][13][14][15] Of the 13 case reports identified, two patients underwent aggressive surgical intervention in addition to traditional pharmacologic regimens. One prior study reports the use of a Billroth II resection with subsequent survival at 24 month follow-up.…”

“…1,2 Though the malignancy is uncommon, recorded metastasis to the stomach is exceedingly rare with only 13 identified cases reported in the literature. [3][4][5][6][7][8][9][10][11][12][13][14][15] In this case report, we discuss the outcomes of a partial gastrectomy for the treatment of symptomatic MCC with gastric metastasis.…”

Merkel Cell Carcinoma with Gastric Metastasis, a Rare Presentation: Case Report and Literature Review

“…Only cases of gastric metastasis from MCC, in the absence of further confounding conditions, were selected. At the end, 20 publications have been considered relevant for the research query (Figure 1) [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35]. The information available for each clinical case (including the case report described herein) regarding the age, gender, ethnicity, primary site, therapy for primary site, time between initial diagnosis/therapy and metastasis presentation, management of metastasis, outcome at time of report, time between metastatic diagnosis and death have been collected and compared.…”