Gas chromatographic determination of toxic quinolizidine alkaloids in blue cohosh Caulophyllum thalictroides (L.) Michx

Betz, Joseph M.; Andrzejewski, Denis; Troy, Annette; Casey, Ryan E.; Obermeyer, William R.; Page, Samuel W.; Woldemariam, Tibebe Z.

doi:10.1002/(sici)1099-1565(199809/10)9:5<232::aid-pca412>3.3.co;2-x

Cited by 4 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two midwives in our sample reported blood pressure fluctuations associated with use of cohoshes in their patients. Cases of severe stomach pain and toxicity have also been reported, 31 and certain blue cohosh constituents are known to cause severe birth defects in cattle and laboratory rats 32 …”

Section: Discussionmentioning

confidence: 99%

Herbal and Other Complementary Medicine Use by Texas Midwives

Bayles

2007

J Midwife Womens Health

View full text Add to dashboard Cite

This cross-sectional survey sought to document complementary and alternative medicine (CAM) use by Texas midwives, as well as to determine whether licensed direct-entry midwives (LMs) and certified nurse-midwives (CNMs) differed significantly in their patterns of use. All respondents (n = 69) indicated that they used, recommended, or referred their clients for at least one CAM therapy during the preceding year. Ninety percent (90%) of respondents used, recommended, or referred their clients for an herbal remedy (not including homeopathic tinctures). Herbal therapies were among the top three modalities recommended for 7 of 12 (58%) clinical indications. Herbs were the most salient CAM therapy used for cervical ripening (83%), followed closely by use for nausea, vomiting, and hyperemesis (80%), and labor induction (77%). Herbal therapies also constituted 50% or more of the CAM therapies used for the following indications: anemia/iron supplementation (70%), perineal healing (66%), and anxiety/stress/fatigue (50%). LM respondents used, recommended, or referred their clients for a greater number of herbal therapies compared to CNMs. While several of the CAM modalities used or recommended by Texas midwives show potential for clinical benefit, few have been studied sufficiently to determine their efficacy or safety during pregnancy.

show abstract

Section: Discussionmentioning

confidence: 99%

Herbal and Other Complementary Medicine Use by Texas Midwives

Bayles

2007

J Midwife Womens Health

View full text Add to dashboard Cite

show abstract

“…In the present study, tissue contractile responses to lower doses of blue cohosh were statistically less than those to larger, indicating that blue cohosh has some dose-dependency. This relationship is likely due to nicotinic cholinergic receptor binding to Nmethylcytisine (Schemmler et al, 1994) as found in Caulophyluum thalactroides (Betz et al, 1998;Ganzera et al, 2003).…”

Section: Discussionmentioning

confidence: 96%

Research Article: Pharmacological effects of the aqueous extract of Caulophyllum thalictroides (blue cohosh) on isolated Mus musculus uteri

Berger

DeGolier

2008

BIOS

View full text Add to dashboard Cite

show abstract

“…Information on 25 NHPs reported in the literature as having effects on blood pressure was summarized in 4 tables; 9 hypertensive NHPs (Tables 1 24-50 and 2 [51][52][53][54][55] ) and 16 hypotensive NHPs (Tables 3 56-69 and 4 38,61,[70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85][86][87][88] ). One NHP (ginseng) was listed as having both hypotensive and hypertensive effects.…”

Section: Data Sourcesmentioning

confidence: 99%

Effects of Natural Health Products on Blood Pressure

Richard

Jurgens

2005

Ann Pharmacother

View full text Add to dashboard Cite

Among published information, there is little definitive evidence with regard to the impact of NHPs on blood pressure. Additionally, effects may vary in a given patient with the formulation and standardization of a particular product. Until research better characterizes the effect of NHPs on blood pressure, patients should be encouraged to talk with their healthcare provider before starting or stopping any herbal product.

show abstract

Gas chromatographic determination of toxic quinolizidine alkaloids in blue cohosh Caulophyllum thalictroides (L.) Michx

Cited by 4 publications

References 0 publications

Herbal and Other Complementary Medicine Use by Texas Midwives

Herbal and Other Complementary Medicine Use by Texas Midwives

Research Article: Pharmacological effects of the aqueous extract of Caulophyllum thalictroides (blue cohosh) on isolated Mus musculus uteri

Effects of Natural Health Products on Blood Pressure

Contact Info

Product

Resources

About