Gangrena de Fournier: Nuestra experiencia en 5 años, revisión de la literatura y valoración del índice de severidad de la Gangrena de Fournier

Morúa, Alejandro García; Lopez, Juan Antonio Acuña; García, José Antonio Guevara; Montelongo, Rafael Martínez; Guerra, Lauro Salvador Gómez

doi:10.4321/s0004-06142009000700003

Cited by 21 publications

(5 citation statements)

References 15 publications

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“…Es necesario identificar hematomas testiculares, hemorragia, tumores, epididimitis, orquitis y abscesos perirrectales, que cursan con una sintomatología similar. Hay series de casos publicadas en las que no se emplearon métodos de estudio por imagen y en los que se señala que debido a la certeza diagnóstica brindada por la clínica y a lo avanzado del cuadro al momento de su ingreso, no se utilizaron 22 . El diagnóstico de GdeF debe establecerse clínicamente.…”

Section: Resultsunclassified

Fascitis necrotizante de las regiones perianal, perineal y genital. Gangrena de Fournier

Motta-Ramírez,

Martínez-Martínez,

Santiago-González

2023

ARM

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Objective: Fournier's gangrene represents a urological surgical emergency. Therefore, the objective is to report our experience emphasizing the role that radiology and imaging have in its identification and follow-up, in addition to assessing its severity index. Material y methods: The clinical records of hospitalized patients diagnosed with Fournier's gangrene in a period from August 2012 to February 2023 at the Central Military Hospital were analyzed. Results: Seven patients with the Fournier's gangrene inclusion criteria were identified. They all identified themselves in the 3 rd . phase (necrosis phase) of the clinical course. All patients achieved a score greater than 6, which definitively established the computed tomography (CT) recognition of the diagnosis of necrotizing fasciitis. Of the 7 patients, 4 (57%) of them achieved an index score by CT of 13; 1 of them scored 10 (14%) and 2 of them scored 9 (29%). Conclusions: An early and timely diagnosis will increase the chances of survival, therefore, the radiologist must know its pathophysiology to specify the diagnosis, define the extent of the disease and call the surgeon without delay. The diagnosis of fascial necrosis remains surgical.

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Section: Resultsunclassified

Fascitis necrotizante de las regiones perianal, perineal y genital. Gangrena de Fournier

Motta-Ramírez,

Martínez-Martínez,

Santiago-González

2023

ARM

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“…Elevated blood glucose levels (above 180 mg/dl) and additional SGLT2 therapy can lead to a state of glycosuria, favoring urinary tract infections. This is associated with local immunodeficiency and deficient microvascularity (T2DM and other comorbidities) which may promote FG in certain patients [19].…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, in our review, B. fragilis was only related to one case and E. coli was not found. In 6 out of 10 cases, the infection is polymicrobial, which means the use of several antibiotics initially, with subsequent modification of the schedule based on culture findings [19]. All blood cultures were negative.…”

Section: Discussionmentioning

confidence: 99%

“…Answering the question of whether the female gender is a risk factor for mortality in patients with FG, it is associated with a higher incidence of inflammation of the retroperitoneal space and the abdominal cavity. The differences between the male and female genital anatomy could be the reason for the rapid spread of the infection to the retroperitoneum and the fatal outcome in women [19][20][21], although more studies are needed to back it up.…”

Section: Discussionmentioning

confidence: 99%

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Fournier’s Gangrene under Sodium–Glucose Cotransporter-2 Inhibitors Therapy in Gynecological Patients

Olave

Moral

Bañón

et al. 2022

IJERPH

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Fournier’s gangrene (FG) is a serious pathology of the soft tissues and fascia of the perineum and genital region with a high morbidity and mortality rate. In recent years, the SGLT-2 inhibitor oral antidiabetic has been related to this entity. According to the new warnings from the main drug agencies, a compilation of cases has been initiated to establish or deny a possible causal relationship. Most of these cases have been reported in men. However, it is important not to underestimate this entity in the gynecological field, since it is extremely serious and requires intense and rapid aggressive treatment based on surgery and empiric antibiotherapy. Later, some cares are needed to involve surgical reconstruction of the defects introduced by debridement. As a result of the low incidence of FG, clinical trials’ data may be insufficient to robustly assess this issue because of the limited numbers of participants. Real-world evidence may help to clarify the association between SGLT2i and FG. The aim of this review is to describe and compare the reported cases of GF in diabetic women who received SGLT2 inhibitors as antiglycemic agents.

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“…Focos no trato urogenital, descritos na literatura, incluem causas variadas: estenoses uretrais, sondagem vesical de demora, abscesso escrotal, orquites, epididimites, abscesso renal, cateterização uretral traumática, cálculos uretrais, cálculos vesicais, câncer vesical, câncer de pênis, massagem prostática e biópsia prostática. No trato digestório foram relatados focos originários em abscessos perianais, carcinomas do cólon e do reto, apendicites e diverticulites agudas, Doença de Crohn, hérnias encarceradas, e perfuração do reto por corpo estranho, sendo, dentre elas, a infecção anorretal a mais frequente associada à causa (GARCIA, et al 2010;MORUA, et al 2009;GOMEZ, et al 2006).…”

Section: Etiologiaunclassified

Síndrome De Fournier: Um Artigo De Revisão

Azevedo

Araújo

Marin

et al. 2016

Connection Line - Revista Eletrônica Do Univag

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A Gangrena de Fournier é uma infecção polimicrobiana ocasionada por microrganismos aeróbios e anaeróbios, que determinam uma fasciíte necrosante rápida e progressiva, comprometendo principalmente a região do períneo e a região genital. Embora qualquer um possa ser acometido pela doença, são afetadas com mais frequência pessoas com algum déficit de imunidade, observa-se também maior prevalência no sexo masculino. Caracteriza-se por ser uma doença de rápida podendo evoluir para Sepse e, se não tratada em tempo hábil poderá progredir para falência múltipla orgânica e até mesmo óbito. O diagnóstico precoce facilita um tratamento eficaz. São medidas de tratamento o desbridamento químico e cirúrgico, antibioticoterapia de amplo espectro e a oxigenoterapia hiperbárica.

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Gangrena de Fournier: Nuestra experiencia en 5 años, revisión de la literatura y valoración del índice de severidad de la Gangrena de Fournier

Abstract: Resumen.

Cited by 21 publications

References 15 publications

Fascitis necrotizante de las regiones perianal, perineal y genital. Gangrena de Fournier

Fascitis necrotizante de las regiones perianal, perineal y genital. Gangrena de Fournier

Fournier’s Gangrene under Sodium–Glucose Cotransporter-2 Inhibitors Therapy in Gynecological Patients

Síndrome De Fournier: Um Artigo De Revisão

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