Gamma knife surgery with a dose of 75 to 76.8 Gray for trigeminal neuralgia

Brisman, Ronald

doi:10.3171/jns.2004.100.5.0848

Cited by 90 publications

(55 citation statements)

References 15 publications

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“…Stereotactic radiosurgery with GKS is an established treatment option for medically refractory idiopathic TN. [1][2][3][4][5][6]8,[10][11][12][13][14][15][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] Indeed, an exponentially increasing number of clinical studies have recently appeared in the literature, reporting on the outcomes in patients undergoing GKS. However, the results vary significantly among different studies; this variation, in combination with the ill-defined outcome criteria and nonstandardized reporting of outcome of nonhomogeneous clinical series (patients with or without previous surgeries and patients with idiopathic or sec-ondary TN), make the interpretation of the reported outcome rates quite confusing.…”

mentioning

confidence: 99%

Gamma Knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications

Fountas¹,

Smith²,

Lee³

et al. 2007

FOC

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Object Stereotactic radiosurgery (SRS) with the Gamma Knife (GK) is a rapidly emerging surgical modality in the management of medically refractory idiopathic trigeminal neuralgia (TN). The current study examines the long-term outcome in patients with drug-resistant idiopathic TN who underwent GK surgery at the authors‘ institution. Methods One hundred and six consecutive patients (38 men and 68 women) with proven medically refractory idiopathic TN were included in this retrospective study. Their ages were 41–82 years (mean 72.3 years). All patients underwent SRS with prescribed maximal radiation doses ranging from 70 to 85 Gy. Isocenters 1–3 were used and plugging was used selectively. The follow-up period was 12–72 months (mean 34.3 months). The patients were divided into 2 groups according to their history of previous surgery. Results The initial response rate in patients with no history of previous surgery was 92.9%; in those who had undergone previous surgery, the initial response rate was 85.7%. At the end of the 1st posttreatment year, an excellent outcome was achieved in 82.5% of patients who had not had previous surgery, and in 69.4% of those who had. The respective outcome rates for the 2nd posttreatment year were 78 and 63.5%, respectively. The most common complication was the development of persistent paresthesia, which occurred in 15.8% of patients with no previous surgery and 16.3% of those with previous surgery. Conclusions Stereotactic radiosurgery with the GK is a safe and effective treatment option for patients with medically refractory idiopathic TN.

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confidence: 99%

Gamma Knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications

Fountas¹,

Smith²,

Lee³

et al. 2007

FOC

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“…It seems that age is not a prognostic factor with "reasonable agreement". In spite of female gender seems to be slightly more frequent in the series (Brisman , 2004;Longhi , 2007;Pollock, 2002;), concerning pain outcome it has been systematically communicated that this variable has not prognostic significance (Aubuchon, 2010;Azar, 2009;Brisman , 2004;Dellaretti, 2008;;Hayashi, 2009;Kimball, 2010;Longhi, 2007;Massager 2007aPark, 2011Riesenburger, 2010;;Rogers, 2000;Sheehan, 2005;Tawk, 2005;Young, 1998): There was found "Consistent agreement" indicating that gender is not a prognostic variable for pain control.…”

Section: Clinical Variablesmentioning

confidence: 81%

“…2.1.6 Atypical neuralgia: More reports found worse pain outcome in patients with atypical neuralgia (Brisman, 2004;Dhople, 2007;Kano,2010;Longhi, 2007;Maesawa, 2001;Rogers, 2000;Varheul, 2010;Young, 1998). Other authors did not found influence of atypical neuralgia on pain improvement (Aubuchon, 2010;Petit, 2003;Pollock, 2002;Regís, 2009;Sheehan, 2005).…”

Section: Pain Distributionmentioning

confidence: 94%

“…Right side seems to be slightly more frequent (Aubuchon, 2010;Cheuk, 2004;Dhople, 2009;Huang, 2008;Kimball, 2010;Pan, 2010;Park, 2011;Regís, 2006;Shaya, 2004;Tawk, 2005), Most authors coincide that the side of the neuralgia has not a prognostic factor (Brisman, 2004;Hayashi, 2009;Kimball, 2010;Little, 2008;Massager , 2007a;;Park, 2011;Riesenburger, 2010;Tawk, 2005). Sheehan (Sheehan, 2005) on the other hand, found better results in patients with right side neuralgia.…”

Section: Sidementioning

confidence: 95%

“…Han (Han, 2009), Sheehan (Sheehan, 2005), Regis (Regís, 2006) and Towk (Tawk, 2005) conversely described worse results in younger patients. In spite of these controversial results, the majority of authors have not found significant influence of the patient age in pain control (Aubuchon, 2010;Azar, 2009;Brisman, 2004;Dellaretti, 2008;Hayashi, 2009;Little, 2008;Longhi, 2007;Massager, 2007a;Park, 2011;Petit, 2003;Riesenburger, 2010;Rogers, 2000;Young, 1998). It seems that age is not a prognostic factor with "reasonable agreement".…”

Section: Clinical Variablesmentioning

confidence: 96%

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