Gamma Glutamyl Transferase Levels In Patients with Acute Coronary Syndrome: A Cross-Sectional Study

Jain, Jyoti; Verma, Navin Kumar; Pradeep, Desmukh

doi:10.5530/jcdr.2017.4.28

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Bawiskar et al reported on clinico-radiological association of serum calcium, ionic calcium and albumin corrected serum calcium in acute ischaemic stroke [23]. Few of the related studies were reviewed [24][25][26][27][28][29][30][31][32][33][34][35][36][37].…”

Section: Discussionmentioning

confidence: 99%

A Study Protocol for Estimating the Association of De Ritis ratio (AST/ALT) with Outcomes in Patients of Acute Ischemic Stroke

Nimkar

Varma

Acharya

et al. 2021

JPRI

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Background: One of the clinical endpoints of atherosclerosis is stroke, the most prominent clinical manifestation of cerebrovascular disease. It is a cerebral blood vessel disease that nourishes the brain. A global health concern is stroke. It is the second most prevalent cause of death worldwide and the fourth leading cause of disability. The underlying pathophysiology in most ischemic strokes is atherosclerosis. Few studies have shown that high AST/ALT ratio was independently corelated with the increased danger of complication and death in cerebrovascular event patients. This research aims to assess the correlation of De Ritis ratio in cases of acute ischaemic stroke at admission and their prognosis at 3 months. Methodology: This will be a observational cross sectional study. About 65 patients with signs suggestive of acute ischemic will be examined. A comprehensive laboratory examination will be carried out. For confirmation of the diagnosis, all patients will undergo CT SCAN or MRI assessment. The primary results of stroke severity on admission will be obtained according to the NIHSS scale. The ranking for NIHSS would be dichotomized to less than 5 and more than 5. For all cases diagnosed with acute ischemic stroke, AST/ALT RATIO will be computed. Data will be analysed with relevant statistical tests. Results Expected: We expect a significant correlation between serum de-Ritis ratio and prognosis of acute ischaemic stroke.

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Section: Discussionmentioning

confidence: 99%

A Study Protocol for Estimating the Association of De Ritis ratio (AST/ALT) with Outcomes in Patients of Acute Ischemic Stroke

Nimkar

Varma

Acharya

et al. 2021

JPRI

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show abstract

“…A study done by Cheng, Bihuan, et al in 2020 showed that high levels of anion gap were associated with poor prognosis in patients with acute kidney injury [13] . Few studies on related aspects of this issue are available [14][15][16][17][18] . The results will be concluded and determined from this study, and will help to indicate the role of anion gap as a prognostic indicator in acute coronary syndrome.…”

Section: Discussionmentioning

confidence: 99%

Role of Anion Gap as a Prognostic Indicator in Acute Coronary Syndrome (ACS)

2020

IJFMT

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Background: Cardiovascular diseases are the leading cause of mortality in India and acute coronary syndrome (ACS) is one of its anomalies, affecting mainly the coronary arterial blood supply and further the functioning of heart muscle. Its subtypes are Non-ST elevation myocardial infarction (NSTEMI), unstable angina, and ST-elevation myocardial infarction (STEMI). There are various diagnostic tools available to detect ACS like; electrocardiography (ECG), Cardiac stress test, Coronary CT angiography, Coronary angiogram and cardiac biomarkers. Yet, tools for assessment of prognosis are scanty and new prognostic tools are always welcomed, one such is anion gap, which can be detected by assessment of certain ions present in the serum, urine or plasma, etc. In this study we will assess the role of anion gap, in the assessment of prognosis in ACS. Objective:1. To estimate anion gap (AG) in cases of acute coronary syndrome (ACS) at the time of diagnosis; 2. To evaluate association of anion gap (AG) with the prognosis of acute coronary syndrome (ACS) Methodology: The study will be conducted in the Department of Medicine of a Rural Tertiary Care Hospital. Estimation of anion gap (AG) in cases of acute coronary syndrome (ACS) will be evaluated at the time of admission and after five days of treatment. Anion gap will be calculated or measured as difference between measured cations (Na+ + K+) and the measured anions (Cl-+ HCO3-) in serum. Any complications during the management will be noted (Heart failure arrhythmias, Hypotension, Reinfarction, Death) will be correlated with anion gap (AG). Chi square test will be applied to evaluate statistical difference between among anion group quartile groups. Results:The study will play a key role in identifying and assessing various other prognostic tools like anion gap, in assessing the severity of disease to some extent in patients with acute coronary syndrome. Conclusion:High value of serum anion gap levels is associated with poorer prognosis of the disease outcome in patients with acute coronary syndrome.

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Gamma Glutamyl Transferase Levels In Patients with Acute Coronary Syndrome: A Cross-Sectional Study

Cited by 2 publications

References 17 publications

A Study Protocol for Estimating the Association of De Ritis ratio (AST/ALT) with Outcomes in Patients of Acute Ischemic Stroke

A Study Protocol for Estimating the Association of De Ritis ratio (AST/ALT) with Outcomes in Patients of Acute Ischemic Stroke

Role of Anion Gap as a Prognostic Indicator in Acute Coronary Syndrome (ACS)

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