Gambaran Patologi Anatomi Pada Babi Landrace Suspect African Swine Fever (Asf) Di Kabupaten Kupang

Abstract

African Swine Fever (ASF) is a viral disease that attacks pigs and to date has caused many pig deaths in Kupang Regency. ASF is caused by a double-stranded DNA virus from the Asfivirus genus and the Asfarviridae family. This research aims to determine the anatomical pathology of the swine landrace suspect ASF. Organ samples were collected from two male landrace pigs and two female landrace pigs, aged 7 months, from Oeltuah Village, Taebenu District and Tarus Village, Central Kupang District, Kupang Regency, NTT. Clinical examinations were carried out on sick animals that were found during the investigation, then necropsied on the dead animals were carried out and continued with anatomical pathology examinations at the Pathology Laboratory, Faculty of Veterinary Medicine, Nusa Cendana University. Anatomical pathology examinations are carried out by observing changes in the structure and appearance of the organs. The necropsy results showed sub-cutaneous ecchymosis hemorrhage in the abdomen, limbs and ears, gastric, intestinal and hepatic hemorrhage, hemorrhagic lymphadenitis in mesenteric lymph nodes, hyperemic splenomegaly, pteckie hemorrhage in the renal capsule,, multifocal hemorrhage in the renal medulla and pulmonary lobe. Based on the observation of clinical symptoms and changes in anatomical pathology, it can be concluded that the death of pigs was suspected to be caused by the suspect ASF.

A Case Study of Pig Diseases in the Special Region of Yogyakarta

“…The incidence of bacterial infection was strongly influenced by various factors, including: traditional management systems, multi-species pig farm mixed with other animals, which are potential sources of transmission of Pasteurella sp. [6]. In addition, The highest population density and poor sanitation were very influence the disease incidence [7].…”

“…According to [9] stated that the disease caused respiratory problems, stunted growth, and economic losses due to decreased living weight and costs of treatment or prevention. The research was conducted by [6] at the Oeba Slaughterhouse, Kupang, East Nusa Tenggara showed that most infection of the pigs was Pasteurella sp. The generally symptoms showed a mild anorexia, cough and dyspnoea.…”

“…In addition, macrophages and neutrophils were also found in the alveoli. [6] stated that the type of bronchopneumonia caused by Pasteurella sp. is bronchopneumonia suppurativa which is characterized by characteristic coagulation necrosis in the alveoli area surrounded by infiltration of neutrophil cells, as well as the accumulation of a number of fibrin in the pulmonary alveoli.…”

Histopathology of Rat Kidney Exposed to Lead Heavy Metal

“…Logam berat timbal yang bersirkulasi dalam darah dapat menimbulkan reaksi pembentukan reactive oxygen species (ROS) dalam jaringan glomerulus maupun tubulus ginjal. Akibat dari peroksidasi sel-sel glomerulus maupun tubulus, menyebabkan terjadinya nekrosis dan nefritis (Sharma et al, 2014).…”

“…Stres oksidatif terjadi apabila ROS (reactive oxygen species) melebihi jumlah antioksidan untuk melindungi sel terhadap molekul-molekul yang teroksidasi (Lopes et al, 2016). Mekanisme stres oksidatif akibat induksi timbal secara umum adalah dengan merusak membran sel, DNA, dan antioksidan baik pada hewan maupun manusia (Sharma et al, 2014). Timbal dapat menjadi radikal bebas karena timbal memiliki atom bebas yang akan melengkapi lapisan luar timbal menjadi lebih stabil dengan mengikat molekul lain dari tubuh (Dewi et al, 2017).…”