Gallbladder bleeding-related severe gastrointestinal bleeding and shock in a case with end-stage renal disease

Abstract

Gallbladder (GB) bleeding is very rare and it is caused by cystic artery aneurysm and rupture, or GB wall rupture. For GB rupture, the typical findings are positive Murphy's sign and jaundice. GB bleeding mostly presented as hemobilia. This is the first case presented with severe GI bleeding because of GB rupture-related GB bleeding. After comparing computed tomography, one gallstone spillage was noticed. In addition to gallstones, uremic coagulopathy also worsens the bleeding condition. This is also the first case that patients with GB spillage-related rupture and bleeding were successfully treated by nonsurgical management. Clinicians should bear in mind the rare causes of GI bleeding. Embolization of the bleeding artery should be attempted as soon as possible.

Acute cholecystitis with intraluminal gallbladder bleeding: Case report and literature review

“…[3,7] Only a small number of cases of hemorrhagic cholecystitis have been reported. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] Intra-luminal bleeding of the gallbladder is in the majority of cases a result of gallbladder wall inflammation that leads to mucosal ulceration with necrosis and is usually associated with the presence of gallstones although acalculose hemorrhagic cholecystitis has also been described in the literature. [3,4] Factors predisposing a patient to spontaneous hemorrhage are trauma, biliary neoplasm, vascular abnormalities, anticoagulation therapy and bleeding diathesis of which use of anticoagulants is predictably the main risk factor for hemorrhagic cholecystits.…”

“…[13] While perforation of the gallbladder wall in the settings of intraluminal bleeding results in hematoperitoneum with hemodynamic instability rapid deteorisation of the patient's condition is to be expected. [7][8][9] Abdominal ultrasound is a diagnostic standard when facing a patient with upper abdominal pain. [1] In the settings of hemorrhagic cholecystitis it can be nonspecific and inaccurate.…”

Gallbladder bleeding along with cholecystocolonic fistula: a case report

“…Gallbladder (GB) bleeding is seldom reported, which mostly manifests as hemobilia. Some cases are caused by cystic artery aneurysm and rupture and others are due to GB rupture [ 3 ]. Gallstones can erode through the gallbladder wall or bile duct into the adjacent portion, resulting in a cholecystocolonic fistula (CCF), which is a rare complication of gallstones with cholecystitis [ 4 ].…”