Gait Deviation Index, Gait Profile Score and Gait Variable Score in children with spastic cerebral palsy: Intra-rater reliability and agreement across two repeated sessions

Rasmussen, Helle Mätzke; Nielsen, Dennis Brandborg; Pedersen, Niels Wisbech; Overgaard, Søren; Holsgaard-Larsen, Anders

doi:10.1016/j.gaitpost.2015.04.019

Cited by 60 publications

(49 citation statements)

References 22 publications

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“…We found an interclass correlation (ICC) of 0.98 and a standard error of measurement (SEM) of 1.05. These results are similar to those of Rasmussen et al [35] who assessed reliability of the GPS by assessing 18 patients with spastic CP on two occasions within a 10 day period and found an ICC of 0.88 and a SEM of 1.09.…”

Section: Discussionsupporting

confidence: 90%

Abnormality of standing posture improves in patients with bilateral spastic cerebral palsy following lower limb surgery

et al. 2017

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Section: Discussionsupporting

confidence: 90%

Abnormality of standing posture improves in patients with bilateral spastic cerebral palsy following lower limb surgery

et al. 2017

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“…This is the first study that provides evidence about spatial-temporal gait parameters after treatment with nabiximols and the first that evaluates the whole kinematic effects in MS after an antispasticity drug treatment. The reliability of the three-dimensional gait analysis is generally considered very high, and the changes in both spatial-temporal and kinematic variables observed are definitely higher than the test-retest variability [24][25][26], thus indicating that the variations in the gait parameters are actually due to the nabiximols treatment.…”

Section: Discussionmentioning

confidence: 99%

Walking improvements with nabiximols in patients with multiple sclerosis

et al. 2015

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Recently, nabiximols was approved as a treatment in MS spasticity. Data leading to approval and clinical use of nabiximols, although widely recognised, are based on subjective scales. Movement analysis procedures would obtain more detailed data about the impact on mobility. The aim of the study was to quantitatively assess the functional modification of gait patterns induced by nabiximols in MS. We evaluated three-dimensional gait analysis (spatial-temporal and kinematic) variation by means of one-way ANOVA. Twenty patients were enrolled-9 male and 11 female-with mean EDSS of 5.3 (SD ± 0.81) and mean reduction of numerical rating scale during nabiximols treatment of 1.88. The spatial-temporal parameters of gait revealed an increased speed (+15 %, p < 0.001), cadence (+6 %, p < 0.001) and stride length (+10 %, p < 0.001) after treatment. Regarding the kinematics data, the Gait Profile Score after treatment was reduced by 10 % (p < 0.001): Significant changes involved the pelvic area, hip rotation and knee flexion-extension. We found that nabiximols is able to improve the speed, cadence and stride length. Furthermore, the dynamics of the proximal segment of the legs and the knee movement results after treatment are closer to the physiologic values.

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“…19 GDI is based upon kinematic data from the gait analysis (step 1) and summarizes the overall gait pathology into a single score when compared with non-pathological gait. 20 The median of five trials for each leg was used to calculate the average of both legs to provide a single index for each child. 20 The median of five trials for each leg was used to calculate the average of both legs to provide a single index for each child.…”

Section: Outcome Measuresmentioning

confidence: 99%

“…20 Furthermore, a minimum clinically important difference in GDI was a priori defined as 7.9, which is equivalent to an improvement of 10%, as suggested by Schwartz et al 24 Therefore, a minimum of 29 participants in each group (n=58) was required with alpha of 0.05 and 80% power. The sample size was based on data from a previous study performed in our laboratory demonstrating a group mean GDI of 79.3 (standard deviation 12.0).…”

Section: Statisticsmentioning

confidence: 99%

Gait analysis for individually tailored interdisciplinary interventions in children with cerebral palsy: a randomized controlled trial

Rasmussen

Pedersen

Overgaard

et al. 2019

Develop Med Child Neuro

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AIM To test the hypothesis that improvements in gait and function following individualized interdisciplinary interventions consisting of physical therapy, orthotics, spasticity management, and orthopaedic surgery using instrumented gait analysis are superior to 'usual care' in children with cerebral palsy (CP).METHOD This was a prospective, single-blind, parallel-group, randomized controlled trial investigating the effectiveness of interventions based on the use of gait analysis. Primary outcome was gait (Gait Deviation Index) and secondary outcomes were walking and patientreported outcome measures of function, disability, and health-related quality of life. Followups were done at 26 weeks (questionnaires) and at the primary end point of 52 weeks (all outcomes). RESULTSSixty participants with CP (39 males, 21 females, mean age 6y 10mo, standard deviation 1y 3mo, range 5y-9y 1mo) in Gross Motor Function Classification System levels I or II, were randomized to interventions with or without gait analysis. No significant or clinically relevant between-group differences in change scores of the primary or secondary outcomes were found. The recommended categories of interventions were dominated by non-surgical interventions and were applied in 36% to 86% of the participants.INTERPRETATION Interventions using gait analysis were not superior to 'usual care' on gait, walking, or patient-reported outcomes in a sample of relatively young and independently walking children with CP not expected to need surgery.

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Gait Deviation Index, Gait Profile Score and Gait Variable Score in children with spastic cerebral palsy: Intra-rater reliability and agreement across two repeated sessions

Cited by 60 publications

References 22 publications

Abnormality of standing posture improves in patients with bilateral spastic cerebral palsy following lower limb surgery

Abnormality of standing posture improves in patients with bilateral spastic cerebral palsy following lower limb surgery

Walking improvements with nabiximols in patients with multiple sclerosis

Gait analysis for individually tailored interdisciplinary interventions in children with cerebral palsy: a randomized controlled trial

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