Gadolinium-based contrast agents: From gadolinium complexes to colloidal systems

Copper‐Based Hybrid Polyion Complexes for Fenton‐Like Reactions

“…Their performances are comparable to a classical homogeneous reaction, although HPICs are easily recyclable by simple dialysis. This study demonstrates that HPIC nano‐objects previously used as templates for the formation of nanomaterials [11] or as contrast agents, [10, 24] have also promising applications as catalytic systems. The ability of HPICs to be formed from different ions or mixture of ions opens promising perspectives to get access to multicatalytic “homogeneous” systems for different reactions (Lewis catalyst, Fenton catalysis.…”

Peptide-Based Soft Hydrogels Modified with Gadolinium Complexes as MRI Contrast Agents

“…Commercial CAs show relaxivity values between 4 and 5 mM −1 s −1 at 20 MHz and 310 K. In the past few years, many efforts have been made to improve CAs performance in terms of relaxivity values, biodistribution profile, and clearance time. One of the proposed strategies is the employment of macromolecular (polymers [9,10] and dendrimers [11,12]) or supramolecular (micelles [13][14][15], liposomes [16,17], nanogels [18,19], nanotubes [20,21], and fibers [22,23]) nanostructures for the delivery of Gd(III)-CAs. Due to their size and to their slow reorientation time, each gadolinium complex embedded in the nanostructure has a relaxivity value 2-5-fold higher in respect of the values associated to classical low molecular weight Gd-complexes.…”

Revisiting the factors influencing the magnetic resonance contrast of Gd2O3 nanoparticles

“…In the meantime, for 9 nm particles, the CA modified GON has a slightly higher relaxivity than the PAA2000 modified one, which was unexpected. 43 Nonetheless, our results appeared to be associated with the acidity and alkalinity on the surface of nanoparticles. We thus determined the isoelectric points (pI) of all the modified GONs and correlated them with the r1 values.…”