Future Perspectives in Glucose Monitoring Sensors

Frontino, Giulio; Meschi, Franco; Bonfanti, Riccardo; Rigamonti, Andrea; Battaglino, Roseila; Favalli, Valeria; Bonura, Clara; Ferro, Giusy; Chiumello, G

doi:10.17925/ee.2013.09.01.21

Cited by 8 publications

(4 citation statements)

References 36 publications

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“…The major difference observed in hypertension trends between these previous studies and the present study may be explained by the fact that the presence or absence of antihypertensive drug use could not be taken into account in our definition of hypertension due to insufficient data in the present study. The declining trend of hypertension risk observed in this study may reflect that although there was an increase in the number of people requiring antihypertensive treatment after the accident, as pointed out in previous studies [ 16 , 17 , 51–55 , 57 , 58 , 59 , 60 ], the blood pressure of those people was well controlled. In fact, adequate control of hypertension is possible because blood pressure can be monitored daily using a home sphygmomanometer after a disaster [ 61 ].…”

Section: Discussionsupporting

confidence: 69%

Comparative risk assessment of non-communicable diseases by evacuation scenario– a retrospective study in the 7 years following the Fukushima Daiichi nuclear power plant accident

Nomura

Murakami

Ozaki

et al. 2021

Global Health Action

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Background : As a result of the Fukushima Daiichi nuclear power plant accident, many residents evacuated and were exposed to changes in their living environment and socioeconomic status, and to persistent stressors. Past studies have suggested the potential for these circumstances to contribute to long-term changes to population health. Objective : The objective of this study was to gain a better understanding of long-term health effects of evacuation, by evaluating the risk of non-communicable diseases among evacuees from Minamisoma City (one of the closest municipalities to the power plant) until 2017. Methods : The study evaluated data from annual health check-ups for residents aged 40–74 years covered by National Health Insurance (who are largely self-employed) from 2010 to 2017 administered by Minamisoma City. Diabetes, hyperlipidemia, and hypertension were defined from the results of blood sampling. Annual changes in age-adjusted prevalence were estimated by evacuation scenario. We also performed an inverse-probability weighting (IPW) analysis to adjust for baseline covariates in 2010 and estimated the differences in the risk of diabetes, hyperlipidemia, and hypertension by evacuation scenario as of the 2017 health check-up in reference to the no-evacuation group. Results : A total of 1,837 individuals were considered in this study. Regardless of evacuation scenario, there was statistical evidence suggesting an upward and a downward trend in diabetes and hypertension from 2010 to 2017, respectively, while hyperlipidemia showed no remarkable change. IPW analyses demonstrated that disease risks in 2017 did not differ significantly among people with different evacuation scenarios. Conclusions : Region-specific factors played an important role in the health effects of the evacuation. Our findings have important implications for the need of an assessment of the health effects of evacuations in more localized manner. Further research in this area will strengthen the communities’ preparedness for future disasters that require mass evacuation.

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Section: Discussionsupporting

confidence: 69%

Comparative risk assessment of non-communicable diseases by evacuation scenario– a retrospective study in the 7 years following the Fukushima Daiichi nuclear power plant accident

Nomura

Murakami

Ozaki

et al. 2021

Global Health Action

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“…50 In contrast, diabetes and hyperlipidaemia are more difficult to control after a disaster; almost all available blood glucose and cholesterol monitoring require invasive procedures, selfmonitoring is less accepted by patients, resulting in reduced patient compliance in diabetes and hyperlipidaemia monitoring and treatment. 51 Previous studies have reported associations between experiences of lifethreatening disaster and reduced chronic health control. 41 The findings of our study show that, regardless of evacuation, there was significantly increased risk of diabetes and hyperlipidaemia more than 3 years after Figure 2 Box plots for the distribution of radiation levels at non-evacuees'/temporary-evacuees' residences by disease status.…”

Section: Discussionmentioning

confidence: 99%

Postnuclear disaster evacuation and chronic health in adults in Fukushima, Japan: a long-term retrospective analysis

et al. 2016

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ObjectiveJapan's 2011 Fukushima Daiichi Nuclear Power Plant incident required the evacuation of over a million people, creating a large displaced population with potentially increased vulnerability in terms of chronic health conditions. We assessed the long-term impact of evacuation on diabetes, hyperlipidaemia and hypertension.ParticipantsWe considered participants in annual public health check-ups from 2008 to 2014, administrated by Minamisoma City and Soma City, located about 10–50 km from the Fukushima nuclear plant.MethodsDisease risks, measured in terms of pre-incident and post-incident relative risks, were examined and compared between evacuees and non-evacuees/temporary-evacuees. We also constructed logistic regression models to assess the impact of evacuation on the disease risks adjusted for covariates.ResultsData from a total of 6406 individuals aged 40–74 years who participated in the check-ups both at baseline (2008–2010) and in one or more post-incident years were analysed. Regardless of evacuation, significant post-incident increases in risk were observed for diabetes and hyperlipidaemia (relative risk: 1.27–1.60 and 1.12–1.30, respectively, depending on evacuation status and post-incident year). After adjustment for covariates, the increase in hyperlipidaemia was significantly greater among evacuees than among non-evacuees/temporary-evacuees (OR 1.18, 95% CI 1.06 to 1.32, p<0.01).ConclusionsThe singularity of this study is that evacuation following the Fukushima disaster was found to be associated with a small increase in long-term hyperlipidaemia risk in adults. Our findings help identify discussion points on disaster planning, including preparedness, response and recovery measures, applicable to future disasters requiring mass evacuation.

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“…1 Self-monitoring of blood glucose limitations are infection risk, and it implies a significant number of daily punctures that are uncomfortable and painful. 3 Another method to obtain glucose measurements is continuous glucose monitoring (CGM). This technology uses a sensor, a glucose oxidase platinum electrode that generates an electrical current generating an average glucose value every 5 minutes in the presence of glucose.…”

Section: Aspects To Consider When Using Rs For Noninvasive Glucose Me...mentioning

confidence: 99%

“…2 Current, GM devices are invasive or minimally invasive, which need a significant number of daily punctures that are uncomfortable, painful, and pose an infection risk. 3,4 Also, they can be costly and uncomfortable to wear. 5 The above limitations explain why people with diabetes do not monitor their glucose levels as often as recommended.…”

Section: Introductionmentioning

confidence: 99%

Noninvasive Glucose Measurements Through Transcutaneous Raman Spectroscopy: A Review

Loyola-Leyva¹,

Hernández-Vidales

Loyola-Rodríguez

et al. 2022

J Diabetes Sci Technol

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Background: People living with diabetes need constant glucose monitoring to avoid health complications. However, they do not monitor their glucose levels as often as recommended, probably because glucose measurement devices can be painful, costly, need testing strips or sensors, require lancing the finger or inserting a sensor with risk of infection, and can be inaccurate or have failures. Therefore, developing new alternatives for noninvasive glucose measurements that overcome these disadvantages is necessary, being Raman spectroscopy (RS) a solution. Objective: This review aims to provide an overview of the current glucose-monitoring technologies and the uses and advantages of RS to improve noninvasive transcutaneously glucose-monitoring devices. Results: The skin has been used to assess glucose levels noninvasively because it is an accessible tissue where glucose can be measured in the interstitial fluid (ISF) in the epidermis (especially in the stratum corneum). The most selected skin sites to apply RS for noninvasive glucose measurements were the nailfold, finger, and forearm because, in these sites, the penetration depth of the excitation light can reach the stratum corneum (10-20 µm) and the ISF. Studies found that RS is a good optical technique to measure glucose noninvasively by comparing glucose levels obtained by RS with those from invasive methods such as glucose meters with testing strips during an oral glucose tolerance test (OGTT). Conclusions: New alternatives for noninvasive glucose measurements that overcome the disadvantages of current devices is necessary, and RS is a possible solution. However, more research is needed to evaluate the stability, accuracy, costs, and acceptance.

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Future Perspectives in Glucose Monitoring Sensors

Cited by 8 publications

References 36 publications

Comparative risk assessment of non-communicable diseases by evacuation scenario– a retrospective study in the 7 years following the Fukushima Daiichi nuclear power plant accident

Comparative risk assessment of non-communicable diseases by evacuation scenario– a retrospective study in the 7 years following the Fukushima Daiichi nuclear power plant accident

Postnuclear disaster evacuation and chronic health in adults in Fukushima, Japan: a long-term retrospective analysis

Noninvasive Glucose Measurements Through Transcutaneous Raman Spectroscopy: A Review

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