Future directions for use guanidine derivatives in veterinary medicine and agricultural production (review)

Abstract

mice amounts to 5283 mg/kg. The value of LD50 at intragastric administration to rats amounts to 6100 mg/kg. This allows attributing aerosol "Metrazol-bio" to the fourth class of danger. The specified cumulation coefficient amounted to 7.4, which allows attributing medication to preparation without cumulative effect. Further studies will relate to the definition of chronic toxicity, embryotoxic and teratogenic properties of "Metrazol-bio".