Fusarium: A rare factor in diabetic foot infection

Abstract

Diabetic foot infections are an important cause of morbidity. In humans, Fusarium causes external infections. A male obese patient at the age of 56 who had been getting treatment in various clinics due to ulceration and lymphedema. Treatment started with tigecycline 50 mg vial 2x1. Alcaligenes faecalis and Proteus vulgaris reproduced. Tigecycline treatment was stopped on the 4th day and piperacillin/tazobactam 4,5 gr vial 3x1 and liposomal amphotericin B 3 mg/kg/day were initiated. In direct microscopic examination, hypes were seen and Fusarium spp. reproduction was detected. Liposomal amphotericin treatment was stopped on the 15th day and voriconazole 200 mg tb po 2x1 was initiated. At the end of one month, the lesions were regressed entirely. It should not be forgotten that despite its scarcity, fungus factors might give rise to diabetic foot infections and patients should be evaluated in terms of fungus infections. J Microbiol Infect Dis 2017; 7(1): 42-45

Fusariumspp.—An Emerging Pathogen in Chronic Diabetic Ulcer: Case Report and Review of the Literature

“…has emerged as a potent opportunistic human pathogen. 7-9,12-14 Authors’ experience is in accordance, with 2 recorded cases of diabetic foot infection with F. solani (unpublished data). However, there are very few reports concerning the species F. oxysporum , particularly in diabetic patients (Table 1).…”

“…is a human opportunistic pathogen that has been gaining emerging importance. 5,8,9 Case Report A 65-year-old man was referred to our unit for recurrence of infected diabetic foot ulcer. The patient had a diagnosis of non-insulin-dependent, reasonably controlled, type 2 DM, for 16 years.…”

Bisifusarium Delphinoides, an Emerging Opportunistic Pathogen in a Burn Patient with Diabetes Mellitus

“…Fusarium solani was isolated from chronic diabetic ulcer in India and Fusarium endophthalmitis in a case of diabetes mellitus was reported in India [19,25]. Fusarium species was documented as a causative factor in diabetic foot infection in Turkey [26]. These suggest that diabetes mellitus can be a determinant of the Fusarium infection.…”

Ulcus Diabetica Hallucis Pedis: The Importance of Timely Treatment.

“…The foot becomes sensitive to trauma as a result sensory, motor and autonomic dysfunction, and there is excessive pressure in the deformed foot, also the development of ischemia. Besides that, the additional risk factors such as atherosclerotic smoking and obesity complicates the treatment [8].…”