Further Problems of Lymphocyte Production

Yoffey, J. M.

doi:10.1111/j.1749-6632.1964.tb40709.x

Cited by 15 publications

(1 citation statement)

References 77 publications

(62 reference statements)

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“…Neither the real nature of these cells nor their method of mobilisation is at present clear. They may be the large lymphocyte stage of the 'Lymphocyte Production Pathway' where lymphocytes pass through the stages of large, medium and finally small lymphocytes (Yoffey 1964). However, 'stress' lymphocytes are not seen in imprints of human lymph nodes (H. B. Goodall, personal communication); but such nodes were obtained from patients at operation or from cadaver, and therefore possibly not representative of the normal state.…”

Section: Discussionmentioning

confidence: 99%

The Effects of p Adrenergic Blockade on the Responses of Leucocyte Counts to Intravenous Epinephrine in Man

Gader

1974

Scandinavian Journal of Haematology

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Changes in blood neutrophil and lymphocyte counts in response to a 30 min i.v. infusion of epinephrine alone and after pretreatment with propranolol (β‐blocking agent) were studied in 7 healthy subjects. Lymphocytes were classified into ‘normal’ and ‘stress' lymphocytes. Propranolol abolished the ‘stress' lymphocyte response to epinephrine but failed to block the ‘normal’ lymphocyte and, in the majority of subjects, the neutrophil responses. This was taken to indicate that the ‘stress' lymphocyte response is β‐adrenergic in type. A working hypothesis which involves both α and β‐receptors separately was suggested for the ‘normal’ lymphocyte response. More work is needed to clarify the nature of neutrophil responses.

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Section: Discussionmentioning

confidence: 99%

The Effects of p Adrenergic Blockade on the Responses of Leucocyte Counts to Intravenous Epinephrine in Man

Gader

1974

Scandinavian Journal of Haematology

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Fine structure of the bone marrow of the chicken and pigeon

Campbell

1967

Journal of Morphology

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The structure of bone marrow from chickens and pigeons was studied with light and electron microscopy. Erythropoiesis occurs in the Iumen of the medullary sinuses. Immature erythroid cells appear to adhere to the sinus wall and may thus be prevented from entering the peripheral circulation.The wall of the medullary sinuses is formed by elongated lining cells, lacking a basement membrane, which are continuous except at sites where blood cells are passing through them.When viewed with the electron microscope, developing heterophil myelocytes, which occur only in the extravascular spaces, possess two populations of granules; one type is globular in content, the other is fibrillar in content. The globular type predominates during all stages of development and appears to be the specific granule.

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