Further chemical constituents from Sinningia canescens and S. leucotricha (Gesneriaceae)

Antitumoral photoinduced effects of crude extract, fractions, and naphthoquinones from Sinningia magnifica (Otto & A. Dietr.) Wiehler (Gesneriaceae) in a bioguided study

“…[8][9][10][11][12] The species of Gesneriaceae are traditionally used for respiratory problems, wounds, fever, inflammation, pain, snake bites, and infectious diseases. 10,12,13,14,15,16 Phytochemical research on Sinninigia species has mainly reported the identification of terpenes, phenolic glycosides, and compounds from the quinone class, some with documented biological activities such as antioxidant, anti-inflammatory properties, and cytotoxic activity for cancer cell lines. 10,12,14,15,16,17,18,19,20,21,22 Sinningia magnifica (Otto & A.…”

“…At least 75 species of herbs comprise the Sinningia genus, most of them native to Brazil 8‐12 . The species of Gesneriaceae are traditionally used for respiratory problems, wounds, fever, inflammation, pain, snake bites, and infectious diseases 10,12,13,14,15,16 …”

“…Phytochemical research on Sinninigia species has mainly reported the identification of terpenes, phenolic glycosides, and compounds from the quinone class, some with documented biological activities such as antioxidant, anti‐inflammatory properties, and cytotoxic activity for cancer cell lines 10,12,14,15,16,17,18,19,20,21,22 . Sinningia magnifica (Otto & A.…”

CHEMICAL CONSTITUENTS OF Sinningia mauroana AND SCREENING OF ITS EXTRACTS FOR ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES

“…1 Until the last decade, the knowledge about the chemical constitution of Sinningia species was scant, with only four species investigated: S. aggregata, S. allagophylla, S. cardinalis e S. speciosa. 2 Since then, new phytochemical studies were carried on S. aggregata 3 and S. allagophylla, 4 and five species were studied for the first time: S. canescens, 5,6 S. hatschbachii, 7 S. leucotricha, 6,8 S. reitzii, 9 e S. warmingii. 10 The chemical profile that arises from these studies shows that the genus is very chemically diverse, producing anthraquinones, naphthoquinones and derivatives, naphthochromenes, terpenoids, flavonoids, cyclohexylethanoids, and phenylethanoid glycosides.…”

“…10 The chemical profile that arises from these studies shows that the genus is very chemically diverse, producing anthraquinones, naphthoquinones and derivatives, naphthochromenes, terpenoids, flavonoids, cyclohexylethanoids, and phenylethanoid glycosides. [2][3][4][5][6][7][8][9][10] Some compounds isolated from Sinningia spp exhibit biological activity. The naphthoquinone dunniol, obtained from S. allagophylla, showed strong cytotoxic activity against glioma (U251), breast (MCF-7), ovarian (OVCAR-3), and ovarian resistant (NCI-ADR/ RES) human tumor cell lines.…”