Further characterization of the constituents of a thai medicinal plant, Zingiber cassumunar Roxb.

Volatile constituents of essential oils isolated from leaf and rhizome of Zingiber cassumunar Roxb.

“…A number of pure compounds isolated from the plants have been shown to possess antimicrobial (Wasuwat et al, 1989;Giwanon et al, 2000;Habsah et al, 2000), topical and oral anti-inflammatory (Masuda and Jitoe, 1994;Kuroyanagi et al, 1980;Tuntiwachwuttikul et al, 1980Tuntiwachwuttikul et al, , 1981Panthong et al, 1990;Ozaki et al, 1991;Pongprayoon et al, 1996;Panthong et al, 1997;Jeenapongsa et al, 2003), antioxidative activity (Masuda and Jitoe, 1994;Kuroyanagi et al, 1980;Tuntiwachwuttikul et al, 1980Tuntiwachwuttikul et al, , 1981Kanjanapothi et al, 1987;Ozaki et al, 1991;Pongprayoon et al, 1997;Habsah et al, 2000) and antihistaminic effect (Piromrat et al, 1986) as well as activity as a smooth-muscle relaxant (Kanjanapothi et al, 1987). The rhizome oil of Z. cassumunar Roxb.…”

Invasion Inhibitors of Human Fibrosarcoma HT 1080 Cells from the Rhizomes of <i>Zingiber cassumunar</i>: Structures of Phenylbutanoids, Cassumunols

“…Interestingly, the cytotoxicity of 12 was found to be weak. On the other hand, (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol (13), (E)-1-(3,4-dimethoxyphenyl)but-1-ene (16), and (E)-1-(2,4,5-trimethoxyphenyl)but-1-ene (17) showed no anti-invasion effects. With regard to structural requirements of phenylbutanoids 11-17 for the activity, the terminal olefins of the side chain moieties on 11 and 12 were suggested to be important.…”

“…The methanolic extract and EtOAc-soluble fraction were found to show potent inhibitory effects on the invasion of HT 1080 cells through Matrigel-coated filters (Table 1), whereas the H 2 O-soluble fraction showed no activity. The EtOAc-soluble fraction was subjected to normal phase and reversed-phase column chro- matographies, and finally HPLC to give cassumunols A (1, 0.0093% from the dried rhizomes), B (2, 0.0026%), C (3, 0.0016%), D (4, 0.013%), E (5, 0.0044%), F (6, 0.017%), G (7, 0.0021%), and H (8, 0.024%) together with phlasins I (9), 12) II, 12) III (10), 12) IV, 12) V, 12) and VI, 12) (E)-1-(3,4-dimethoxyphenyl)buta-1,3-diene (11), 12,13) (E)-1-(2,4,5-trimethoxyphenyl)buta-1,3-diene (12), 12,13) (Z)-1-(2,4,5-trimethoxyphenyl)buta-1,3-diene (0.0057%), 14) (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol (13), 12,15) (E)-4-(3,4-dimethoxyphenyl)but-3-enyl acetate (14), 12,16) (E)-4-(3,4-dimethoxyphenyl)but-3-ene-1,2-diol (15, 0.021%), 16) (E)-1-(3,4-dimethoxyphenyl)but-1-ene (16), 12,17) (E)-1-(2,4,5-trimethoxyphenyl)but-1-ene (17), 12,17) 12,17) (Ϯ)-cis-3-(2,4,5-trimethoxyphenyl)-4-[(E)-2,4,5-trimethoxystyryl]cyclohex-1-ene (19), 12,17) (Ϯ)-trans-3-(3,4-dimethoxy- 18) (E)-3-(2.4, 5-trimethoxyphenyl)propenal (0.0012%), 19) cassumunaquinones 1 12,20) and 2, 12,20) curcumin, 12,21,22) cassumunarins A (0.0080%) …”

Assessment of genetic diversity in cassumunar ginger (Zingiber cassumunar Roxb.) in Thailand using AFLP markers

“…The essential oil from the rhizome is used for reducing inflammation from injuries, sprains in muscles and joint issues. The results from pharmacological study show that the essential oil has several properties, such as an antiseptic, antitoxic and strong anti-inflammatory effect (Kuroyanagi et al 1980, Jeenapongsa et al 2003, Panthong et al 1990, 1997, Tuntiwachwuttikul et al 1980, 1981. With the rising popularity of herbal products as drugs and cosmetic being reported (Akerele 1993, Cupp 1999, Riewpaiboon 2006, Z. cassumunar has high potential to become a new commercially valuable plant.…”