Fungiurie bei Krebspatienten. Analyse der Risikofaktoren, des klinischen Bildes und des Verlaufs bei 50 Patienten

Oravcova, E.; Lacka, J.; Drgoňa, Luboš; Studena, M.; Ševčíková, Ľudmila; Špánik, S.; Svec, J; Kukuckova, E.; Grey, E.; Silva, J; Krčméry, V.

doi:10.1007/bf01743368

Cited by 16 publications

(13 citation statements)

References 6 publications

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“…Fungal nosocomial infection has become an important problem on the past decade (Oravcova et al 1996). In the present study, candiduria was detected in 44.4% (68/ 153) of the ICU patients.…”

Section: Discussionsupporting

confidence: 52%

Candida colonization in intensive care unit patients' urine

Passos

Sales

Maciel

et al. 2005

Mem. Inst. Oswaldo Cruz

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“…Fungal nosocomial infection has become an important problem on the past decade (Oravcova et al 1996). In the present study, candiduria was detected in 44.4% (68/ 153) of the ICU patients.…”

Section: Discussionsupporting

confidence: 52%

Candida colonization in intensive care unit patients' urine

Passos

Sales

Maciel

et al. 2005

Mem. Inst. Oswaldo Cruz

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“…The pathogenesis of candidal UTI has been relatively well characterized and many risk factors have been identified [10][11][12]. In our study, most of the pediatric patients had underlying diseases, mainly urinary tract abnormalities and prematurity.…”

Section: Discussionmentioning

confidence: 77%

Hospital-associated funguria: analysis of risk factors, clinical presentation and outcome

Carvalho¹,

Guimarães²,

Junior³

et al. 2001

Braz J Infect Dis

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Fungal urinary tract infections are an increasing problem in hospitalized patients. Funguria may be a result of contamination of the urine specimen, colonization of the urinary tract, or may be indicative of true invasive infection. In this study, we report the risk factors, clinical features, treatments and outcome in a group of 68 hospitalized patients (adults and children) with fungal isolates recovered from 103 urinary samples. Underlying medical conditions were present in most patients. In the pediatric group, urinary tract abnormalities (86%) and prematurity (19%) accounted for the majority of the cases. Diabetes mellitus (28%), nephrolithiasis, and benign prostatic hyperplasia were the most common diseases in adults. Indwelling urethral catheters were noted in 38% of the pediatric patients and in 43% of adults during hospitalization. Candida albicans strains were responsible for 97% and 75% of positive cultures in children and adults, respectively. Symptoms such as fever, dysuria, frequency and flank pain were generally absent in both groups. Fluconazole was the most frequent antifungal utilized (61%) in children and ketoconazole in the adult group (42%). Removing the urinary catheter was attempted in 6 pediatric patients (29%) and in only 8 adults (17%). One patient (4%) in the pediatric group died compared to 10 in the adult group (21%, p=0.04). Successful diagnosis and treatment of funguria depends on a clear understanding of the risk factors and awareness of fungal epidemiology.

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“…3 At the time of candiduria diagnosis. 4 In the month prior to candiduria diagnosis. 5 Immunosuppressive regimens such as tacrolimus and tumour necrosis factor inhibitor.…”

Section: Resultsmentioning

confidence: 99%

Candiduria in haematologic malignancy patients without a urinary catheter: nothing more than a frailty marker?

Georgiadou

Tarrand²,

Sipsas

et al. 2012

Mycoses

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Summary Background There is scarcity of data regarding significance of candiduria in patients with hematologic malignancies and its association with invasive candidiasis. Patients and Methods To that end, we retrospectively evaluated all hospitalized, non-intensive care unit patients with hematologic malignancies and candiduria during a 10-year period (2001-2011). To decrease the possibility of bladder colonization and sample contamination, we excluded all patients with candiduria who had urinary catheters and those with concomitant bacteriuria. Results Twenty-four such patients (21 females) were identified, with median age at diagnosis 62 years (range, 20-82 years). Acute leukemia was the most common underlying disease (54%); 62% of these cases were not in remission. Twenty-nine % of the patients had diabetes mellitus and 25% were neutropenic. The most common isolated Candida species was Candida glabrata (37%), followed by Candida albicans (29%). Only 8% of them had urinary tract infection symptoms. However, 88% received systemic antifungals. Candidemia and crude mortality rates at 4 weeks were low (4% and 12%, respectively). Conclusions Isolated candiduria in patients with hematologic malignancies has risk factors similar to those in other hospitalized patients, and it does not seem to be a strong predictor of subsequent invasive candidiasis.

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Fungiurie bei Krebspatienten. Analyse der Risikofaktoren, des klinischen Bildes und des Verlaufs bei 50 Patienten

Cited by 16 publications

References 6 publications

Candida colonization in intensive care unit patients' urine

Candida colonization in intensive care unit patients' urine

Hospital-associated funguria: analysis of risk factors, clinical presentation and outcome

Candiduria in haematologic malignancy patients without a urinary catheter: nothing more than a frailty marker?

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