Fungicidal activities of camptothecin semisynthetic derivatives against Colletotrichum gloeosporioides in vitro and in mango fruit

Feng, Gang; Zhang, Xiaoshuai; Zhang, Zhengke; Ye, Huo-Chun; Liu, Ying‐Qian; Yang, Guan‐Zhou; Cheng, Chen; Chen, Min; Yan, Chao; Wang, Lanying; Zhang, Junxiang; Zhang, Jing

doi:10.1016/j.postharvbio.2018.09.019

Cited by 34 publications

(18 citation statements)

References 30 publications

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“…In this study, MIC of PD was taken into account with respect to its different concentrations against the fungal radial growth (mm) and compared to distilled water and ethanol following the protocol of Khan et al [ 22 ] and Suwanamornlert et al [ 25 ]. Percent growth inhibition (PI) of each concentration of the propyl disulfide was calculated with the following formula [ 3 , 22 ].

where C = mycelial growth diameter of the control; I = initial mycelial plug diameter (5 mm) and T = mycelial growth diameter of the pathogen exposed to propyl disulfide at each concentration.…”

Section: Methodsmentioning

confidence: 99%

“…Anthracnose can be controlled to a great extent by the applications of synthetic fungicides such as benomyl, carbendazim, thiabendazole, prochloraz, dithiocarbamate and azoles. Nonetheless, numerous adverse effects are associated with synthetic fungicides, such as toxicity, environmental pollution and potential risks to human health [ 2 , 3 , 4 , 5 ]. These negative effects have increased consumer awareness of food safety.…”

Section: Introductionmentioning

confidence: 99%

“…Plant extracts such as aroma compounds ( trans -cinnamaldehyde, citral, and phenylacetaldehyde [ 11 ], Mentha piperita L. essential oil (MPEO) [ 12 ], volatile organic compounds [ 2 ], essential oil from Cymbopogon citratus (D.C. ex Nees) Stapf [ 13 ], and essential oil extracted from Cympopogon citratus and Lippia rehmannii [ 14 ] have suppressed anthracnose in mango fruit. Feng et al [ 3 ] evaluated the antifungal activity of camptothecin (a naturally occurring quinoline alkaloid having a high pesticidal activity) against C. gloeosporioides causing anthracnose disease in mango. Dessalegn et al [ 15 ] evaluated the plant defense-inducing chemicals (PDIC) combined with postharvest treatments with inorganic salts and hot water to prevent mango’s anthracnose.…”

Section: Introductionmentioning

confidence: 99%

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Antifungal Activity of Propyl Disulfide from Neem (Azadirachta indica) in Vapor and Agar Diffusion Assays against Anthracnose Pathogens (Colletotrichum gloeosporioides and Colletotrichum acutatum) in Mango Fruit

et al. 2021

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Microorganisms causing anthracnose diseases have a medium to a high level of resistance to the existing fungicides. This study aimed to investigate neem plant extract (propyl disulfide, PD) as an alternative to the current fungicides against mango’s anthracnose. Microorganisms were isolated from decayed mango and identified as Colletotrichum gloeosporioides and Colletotrichum acutatum. Next, a pathogenicity test was conducted and after fulfilling Koch’s postulates, fungi were reisolated from these symptomatic fruits and we thus obtained pure cultures. Then, different concentrations of PD were used against these fungi in vapor and agar diffusion assays. Ethanol and distilled water were served as control treatments. PD significantly (p ≤ 0.05) inhibited more of the mycelial growth of these fungi than both controls. The antifungal activity of PD increased with increasing concentrations. The vapor diffusion assay was more effective in inhibiting the mycelial growth of these fungi than the agar diffusion assay. A good fit (R2, 0.950) of the experimental data in the Gompertz growth model and a significant difference in the model parameters, i.e., lag phase (λ), stationary phase (A) and mycelial growth rate, further showed the antifungal efficacy of PD. Therefore, PD could be the best antimicrobial compound against a wide range of microorganisms.

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where C = mycelial growth diameter of the control; I = initial mycelial plug diameter (5 mm) and T = mycelial growth diameter of the pathogen exposed to propyl disulfide at each concentration.…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Antifungal Activity of Propyl Disulfide from Neem (Azadirachta indica) in Vapor and Agar Diffusion Assays against Anthracnose Pathogens (Colletotrichum gloeosporioides and Colletotrichum acutatum) in Mango Fruit

et al. 2021

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“…The hyphal growth of Foc TR4 treated with Streptomyces extracts was observed according to the method of Feng et al (2019) . A mycelial disk (4 mm diameter) was taken from the periphery of a colony growing on the PDA medium with 2 × EC 50 of extracts and incubated at 28°C for 24 h. 10% of DMSO treatment was used as a negative control.…”

Section: Methodsmentioning

confidence: 99%

Newly Isolated Streptomyces sp. JBS5-6 as a Potential Biocontrol Agent to Control Banana Fusarium Wilt: Genome Sequencing and Secondary Metabolite Cluster Profiles

et al. 2020

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Banana is a key staple food and fruit in countries all over the world. However, the development of the global banana industry is seriously threatened by Fusarium wilt disease, which is caused by Fusarium oxysporum f. sp. cubense (Foc). In particular, Foc tropical race 4 (Foc TR4) could infect more than 80% of global banana and plantain crops. Until now, there were no commercial chemicals or resistant cultivars available to control the disease. Biological control using actinomycetes is considered a promising strategy. In this study, 88 actinomycetes were isolated from a banana orchard without symptoms of Fusarium wilt disease for more than 10 years. An actinobacterial strain labeled as JBS5-6 has exhibited strong antifungal activities against Foc TR4 and other selected 10 phytopathogenic fungi. Based on phenotypic and biochemical traits as well as complete genome analysis, strain JBS5-6 was assigned to Streptomyces violaceusniger. Extracts of the strain inhibited the mycelial growth and spore germination of Foc TR4 by destroying membrane integrity and the ultrastructure of cells. The complete genome of strain JBS5-6 was sequenced and revealed a number of key function gene clusters that contribute to the biosynthesis of active secondary metabolites. Sixteen chemical compounds were further identified by gas chromatography-mass spectrometry (GC-MS). 5-hydroxymethyl-2-furancarboxaldehyde was one of the dominant components in strain JBS5-6 extracts. Moreover, fermentation broth of strain JBS5-6 significantly reduced the disease index of banana seedlings by inhibiting the infection of Foc TR4 in a pot experiment. Hence, strain JBS5-6 is a potential biocontrol agent for the management of disease and the exploitation of biofertilizer.

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“…From the pathogen, it is necessary to know the genus and the species as well as their concentration found at pre-and post-harvest stages. On the part of the fungicide, it is necessary to know the mode and site of action, as well as the maximum residual limit (MRL) ( Table 1) permitted on fruits and specific regulations where the fruit will be exported [16]. In Table 1, some fungicides used for post-harvest disease of tropical and subtropical fruit diseases are listed.…”

Section: Chemical Methods: Applications For Post-harvest Disease Manamentioning

confidence: 99%

Alternative Eco-Friendly Methods in the Control of Post-Harvest Decay of Tropical and Subtropical Fruits

González-Estrada¹,

Blancas‐Benítez²,

Velázquez-Estrada³

et al. 2020

Modern Fruit Industry

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The effectiveness on several fruits by the application of alternative methods against fungi is summarized in the present chapter. Several investigations have reported the efficacy of these technologies for controlling fungal infections. Currently, high post-harvest loses have been reported due to several factors such as inefficient management, lack of training for farmers, and problems with appropriate conditions for storage of fruits and vegetables. Even now, in many countries, post-harvest disease control is led by the application of chemical fungicides. However, in this time, awareness about fungi resistance, environmental, and health issues has led to the research of eco-friendly and effective alternatives for disease management. The pathogen establishment on fruits can be affected by the application of GRAS compounds like chitosan, essential oils, salts, among others; besides, their efficacy can be enhanced by their combination with other technologies like ultrasound. Thus, the applications of these alternatives are suitable approaches for post-harvest management of fruits.

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Fungicidal activities of camptothecin semisynthetic derivatives against Colletotrichum gloeosporioides in vitro and in mango fruit

Cited by 34 publications

References 30 publications

Antifungal Activity of Propyl Disulfide from Neem (Azadirachta indica) in Vapor and Agar Diffusion Assays against Anthracnose Pathogens (Colletotrichum gloeosporioides and Colletotrichum acutatum) in Mango Fruit

Antifungal Activity of Propyl Disulfide from Neem (Azadirachta indica) in Vapor and Agar Diffusion Assays against Anthracnose Pathogens (Colletotrichum gloeosporioides and Colletotrichum acutatum) in Mango Fruit

Newly Isolated Streptomyces sp. JBS5-6 as a Potential Biocontrol Agent to Control Banana Fusarium Wilt: Genome Sequencing and Secondary Metabolite Cluster Profiles

Alternative Eco-Friendly Methods in the Control of Post-Harvest Decay of Tropical and Subtropical Fruits

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