Fungal melanonychia and <i>Exophiala dermatitidis</i>

Schiavo, Ada Lo; Gambardella, Alessio; Caccavale, Stefano

doi:10.1111/j.1439-0507.2012.02217.x

Cited by 3 publications

(20 citation statements)

References 5 publications

(7 reference statements)

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“…The fungus develops a black color in Sabouraud dextrose agar, typically after 3 days, and can grow in temperatures up to 41°C. However, growth is inhibited in the presence of creatinine or nitrites as the sole source of nitrogen . Given that such confirmatory testing does not routinely take place, and that the fungus can have a yeast‐like appearance with conventional staining, misidentification as Candida species or Cryptococcus species has been reported .…”

Section: Discussionmentioning

confidence: 99%

Emerging pathogen in immunocompromised hosts: Exophiala dermatitidis mycosis in graft‐versus‐host disease

Chalkias

Alonso

Levine

et al. 2014

Transplant Infectious Dis

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Infection with the dematiaceous environmental fungus Exophiala, an emerging pathogen in immunocompromised individuals, poses a diagnostic and therapeutic challenge. Herein, we report the first Exophiala dermatitidis fungemia case, to our knowledge, in an allogeneic hematopoietic stem cell transplant patient with graft-versus-host disease, expanding the clinical setting where Exophiala species mycosis should be suspected.

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Section: Discussionmentioning

confidence: 99%

Emerging pathogen in immunocompromised hosts: Exophiala dermatitidis mycosis in graft‐versus‐host disease

Chalkias

Alonso

Levine

et al. 2014

Transplant Infectious Dis

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“…In terms of total cases, 44% (n = 59) of them were women and 56% (n = 74) represented men. The mean age of presentation was 45.4 years in a range of 9 to 87 years [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ].…”

Section: Resultsmentioning

confidence: 99%

“…In terms of occupations, 95% (n = 126) did not have such information, the remaining 5% (n = 7) corresponded to green tea leaf pickers 1.5% (n = 2), activities related to gardening 2% (n = 3), farmers 0.75% (n = 1) and magistrates 0.75% (n = 1) [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ].…”

Section: Resultsmentioning

confidence: 99%

“…The following background were identified: 11.3% (n = 15) of the cases were related to migration 3.8% (n = 5), cancer 3% (n = 4), nail trauma 1.5% (n = 2), antifungals 0.8% (n = 1), ethnic pigmentation 0.8% (n = 1), longitudinal melanonychia 0.8% (n = 1) and outdoor activity 0.8% (n = 1) [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ].…”

Section: Resultsmentioning

confidence: 99%

“…Likewise, present comorbidities included systemic diseases 26% (n = 34), mycosis 2% (n = 3), cancer 2% (n = 3), immunosuppression states 2% (n = 3) and others 2% (n = 2); 16% (n = 21) reported themselves as healthy; and in 50% (n = 67), pertinent information regarding medical history was not provided. The average evolution time was 1.71 years with a range of 0.08 to 10.6 years [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ].…”

Section: Resultsmentioning

confidence: 99%

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Fungal Melanonychia: A Systematic Review

Rodríguez-Cerdeira,

Martínez-Herrera,

Cortés-López

et al. 2024

Microorganisms

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Fungal melanonychia is an uncommon condition, most typically caused by opportunistic melanin-producing pigmented filamentous fungi in the nail plate. In the present study, the clinical characteristics of patients diagnosed with fungal melanonychia were analyzed through a systematic review of cases reported in the literature. The MESH terms used for the search were “melanonychia” AND “fungal” OR “fungi” through four databases: PubMed, SciELO, Google scholar and SCOPUS. After discarding inadequate articles using the exclusion criteria, 33 articles with 133 cases were analyzed, of which 44% were women, 56% were men and the age range was between 9 and 87 years. The majority of cases were reported in Turkey followed by Korea and Italy. Frequent causal agents detected were Trichophyton rubrum as non-dematiaceous in 55% and Neoscytalidium dimidiatum as dematiaceous in 8%. Predisposing factors included nail trauma, migration history, employment and/or outdoor activities. Involvement in a single nail was presented in 45% of the cases, while more than one affected nail was identified in 21%, with a range of 2 to 10 nails. Regarding the clinical classification, 41% evidenced more than one type of melanonychia, 21% corresponded to the longitudinal pattern and 13% was of total diffuse type. Likewise, the usual dermoscopic pattern was multicolor pigmentation. It is concluded that fungal melanonychia is an uncommon variant of onychomycosis and the differential diagnosis is broad, which highlights the complexity of this disease.

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Melanonychia

Haneke

2018

Scher and Daniel's Nails

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Fungal melanonychia and Exophiala dermatitidis

Cited by 3 publications

References 5 publications

Emerging pathogen in immunocompromised hosts: Exophiala dermatitidis mycosis in graft‐versus‐host disease

Emerging pathogen in immunocompromised hosts: Exophiala dermatitidis mycosis in graft‐versus‐host disease

Fungal Melanonychia: A Systematic Review

Melanonychia

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