Functions of amine oxidases in plant development and defence

Cona, Alessandra; Rea, Giuseppina; Angelini, Riccardo; Federico, Rodolfo; Tavladoraki, Paraskevi

doi:10.1016/j.tplants.2005.12.009

Cited by 545 publications

(476 citation statements)

References 79 publications

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“…CuAOs oxidize Put at the primary amino group producing 4-aminobutyraldehyde (ABAL), hydrogen peroxide (H 2 O 2 ), and ammonia (Medda et al, 2009). PAOs catalyze the oxidation of Spm, Spd, and/or their acetylated derivatives at the secondary amino group (Cona et al, 2006;Angelini et al, 2010). The chemical nature of PAO reaction products depends on the enzyme source and reflects the mode of substrate oxidation.…”

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confidence: 99%

Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

et al. 2011

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Spermidine (Spd) treatment inhibited root cell elongation, promoted deposition of phenolics in cell walls of rhizodermis, xylem elements, and vascular parenchyma, and resulted in a higher number of cells resting in G 1 and G 2 phases in the maize (Zea mays) primary root apex. Furthermore, Spd treatment induced nuclear condensation and DNA fragmentation as well as precocious differentiation and cell death in both early metaxylem and late metaxylem precursors. Treatment with either N-prenylagmatine, a selective inhibitor of polyamine oxidase (PAO) enzyme activity, or N,N 1 -dimethylthiourea, a hydrogen peroxide (H 2 O 2 ) scavenger, reverted Spd-induced autofluorescence intensification, DNA fragmentation, inhibition of root cell elongation, as well as reduction of percentage of nuclei in S phase. Transmission electron microscopy showed that N-prenylagmatine inhibited the differentiation of the secondary wall of early and late metaxylem elements, and xylem parenchymal cells. Moreover, although root growth and xylem differentiation in antisense PAO tobacco (Nicotiana tabacum) plants were unaltered, overexpression of maize PAO (SZmPAO) as well as down-regulation of the gene encoding S-adenosyl-L-methionine decarboxylase via RNAi in tobacco plants promoted vascular cell differentiation and induced programmed cell death in root cap cells. Furthermore, following Spd treatment in maize and ZmPAO overexpression in tobacco, the in vivo H 2 O 2 production was enhanced in xylem tissues. Overall, our results suggest that, after Spd supply or PAO overexpression, H 2 O 2 derived from polyamine catabolism behaves as a signal for secondary wall deposition and for induction of developmental programmed cell death.

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Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

et al. 2011

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“…21,22 An increase in DAO activity leads to generation of hydrogen peroxide. 6 This compound may lead to subsequent triggering of programmed cell death. A programmed cell death may be taking place in tissues surrounding nodules, which may provide an extra source of carbon and nitrogen for the growing plantlets.…”

Section: Discussionmentioning

confidence: 99%

“…As long as the ultrastructure of plastid membranes hydrogen peroxide or diazabicyclononane, diamine propane and hydrogen peroxide, respectively. 6 Plant amine oxidases regulate cellular levels of PAs and contribute to important physiological processes through their reaction products. 6 In particular, 4-aminobutanal can be further metabolized to γ-aminobutyric acid (GABA), a non-protein amino acid that can be also produced by cytosolic glutamate decarboxylase.…”

Section: Adc Accumulation Throughout Organogenic Nodule Formationmentioning

confidence: 99%

“…6 Plant amine oxidases regulate cellular levels of PAs and contribute to important physiological processes through their reaction products. 6 In particular, 4-aminobutanal can be further metabolized to γ-aminobutyric acid (GABA), a non-protein amino acid that can be also produced by cytosolic glutamate decarboxylase. 6 The relative proportions of free and conjugated PAs varied from species to species.…”

Section: Adc Accumulation Throughout Organogenic Nodule Formationmentioning

confidence: 99%

“…6 In particular, 4-aminobutanal can be further metabolized to γ-aminobutyric acid (GABA), a non-protein amino acid that can be also produced by cytosolic glutamate decarboxylase. 6 The relative proportions of free and conjugated PAs varied from species to species. Compared to the intensive attention which has been focused on changes in free PAs in response to stress, alteration of the conjugated form has been less well characterized although stress-induced accumulation of conjugated PAs has been reported in reference 7 and 8.…”

Section: Adc Accumulation Throughout Organogenic Nodule Formationmentioning

confidence: 99%

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