Functionalized chitosan/spherical nanocellulose-based hydrogel with superior antibacterial efficiency for wound healing

Biocompatible, bacteria-targeting resveratrol nanoparticles fabricated by Mannich molecular condensation for accelerating infected wound healing

“…18,56 They have been widely used for wound healing due to their antimicrobial properties, effectively attenuating tissue inflammation and promoting collagen deposition. 57 A schematic illustration of the formation of carboxymethyl chitosan-(4aminophenyl)boronic acid (CMC-PBA) hydrogels was shown in Fig. 6(a).…”

Recent advances in adhesive materials used in the biomedical field: adhesive properties, mechanism, and applications

“…CS is a valuable drug delivery agent due to its excellent biological and adhesive properties. 123,124 Due to its advantages of stability, good biodegradability, and low toxicity in the stomach, CS is often used to protect unstable drugs, such as polyphenols, from gastrointestinal enzyme (GIT) degradation in the gastrointestinal tract, and to enhance the absorption of therapeutic agents. 125,126 CS binds closely to polyphenols via electrostatic interactions, which limits the accessibility of polyphenols in the stomach and small intestine, thereby improving the bioavailability of polyphenols in the presence of low pH and various digestive enzymes.…”

Recent progress of antibacterial hydrogel materials for biomedical applications

“…17a). For skin regeneration, Patel et al 285 synthesized an injectable viscous spherical nanocellulose (s-NC) -enhanced carboxymethyl chitosan hydrogel for rapid skin regeneration. Compared to pure polymer hydrogels, enhanced conductivity, skin regeneration potential and improved antibacterial activity were observed in hydrogels supplemented with s-NC.…”