Functionality of natural killer cells from end-stage cancer patients exposed to coherent electromagnetic fields

Abstract

The main objective of our study is to investigate whether an enhancement of the immune system in end-stage cancer patients is achieved by exposure to coherent electromagnetic fields. For this reason, 15 end-stage cancer patients were exposed at low intensity, coherent electromagnetic fields at radiofrequencies ranging from 600 kHz-729 Hz, for 8 h/day, 6 days/week for 4 weeks. NKs number and cytotoxicity of NK T-lymphocytes versus K562 cancer cell line were estimated by flow cytometry, before and after exposure. Data showed that the exposure of the end-stage cancer patients to the coherent electromagnetic fields resulted in a significant increase of the number and the cytotoxicity of the NK T-lymphocytes against cancer cells, in all patients. Exposure to coherent EMFs at radiofrequencies increases the number and cytotoxicity of NK T-lymphocytes, which may contribute to the improvement of cancer patients' status.

A review on the use of magnetic fields and ultrasound for non-invasive cancer treatment

“…PMF have been used to actuate localized hyperthermia in the tissues where magnetic nanoparticles (MNPs) have been accumulated [27] . PMF treatment has also been advocated for advanced stage of cancer (Stage 3 and 4) primarily because of their intolerance towards chemotherapy due to decreased functionality of several organs [28] . Extremely low frequency PMF has also been shown to inhibit murine malignant tumor growth by arresting neoangiogenesis required for tumor growth [29] .…”

A Review on Chitosan’s Uses as Biomaterial: Tissue Engineering, Drug Delivery Systems and Cancer Treatment

“…Hyperthermia consists of an anti-cancer treatment in which an exogenous energy source is used to promote the healing of the tumors since this heat can increase the therapeutic window of radiotherapy and/or chemotherapy by sensitizing the tumors to these therapies, in addition to the possibility of directly killing cancer cells [365][366][367].…”

“…Pulsed magnetic fields (PMFs) were utilized to activate localized hyperthermia in the tissues in which accumulations of magnetic nanoparticles (MNPs) were present [364]. Due to the intolerance to chemotherapy and decreased functionality of several organs presented by advanced cancer patients (stages 3 and 4), treatment with PMF has been suggested for these cases [365].…”

Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology

“…Surgical techniques, such as minimally invasive surgery, also result in pain, fatigue, appetite loss, swelling and bruising around the site of surgery, bleeding, infection, lymphedema, and organ dysfunction . Numerous studies support the development of new treatments in oncology to be added to the traditional protocols to increase the effectiveness of available treatments, reducing side effect profile, and the patients' quality of life . Such resources include traditional Chinese medicine, Ayurvedic medicine, homeopathy, and naturopathy .…”