Functionalisation of MWCNTs with piperazine and dopamine derivatives and their potential antibacterial activity

Abstract

Functionalised multi-walled carbon nanotubes (MWCNTs) are exclusively used in antibacterial activity due to their high aspect ratio and surface penetration characteristics. This study reports the synthesis of piperazine and dopamine functionalised MWCNTs to investigate antibacterial activity against strains like Staphylococcus aureus and Micrococcus luteus. MWCNTs were activated through acid oxidation and then refluxed at 75°C for 10 and 8 h in the presence of piperazine and dopamine, respectively. The functionalised MWCNTs were characterised by scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray diffraction and Raman spectroscopy. Moreover, functionalised MWCNTs were subjected to zone inhibition assay on agar plates. Results revealed the significant antibacterial activity against various bacteria up to 50%. Similarly, it was observed that the effect of different solvents, such as dimethyl formamide (DMF) and dimethyl sulfoxide (DMSO) was non-prevalent to the bacterial zone of inhibition. Such facile nano-modifications provide passage to nano-antibacterials for advanced studies.

Ni(II)-Complex Anchored onto Magnetically Separable Oxidized Single-Walled Carbon Nanohorn: A DFT-Supported Mechanistic Approach for Hydrogen-Borrowing Quinoxaline Synthesis

“…The observed Raman modes at A 1g (=700 cm –1 ), E g (=329 cm –1 ), T 2g (3) (=579 cm –1 ), T 2g (2) (=483 cm –1 ), and T 2g (1) (=213 cm –1 ) indicate the proper surface modification-functionalized FSWCNHs by the NiFe 2 O 4 magnetic material. The Raman spectrum of FNHDNi in Figure C exhibits two less intense bands, nearly 2704 and 2975 cm –1 , which can be assigned to the intrinsic CH 2 stretching band directly connected to the amide linkage of l -dopa . Again, the presence of the characteristic peak for the azomethine stretch at 1650 cm –1 clearly suggests the successful amalgamation of l -dopa and complex 1 over the FSWCNHs@NiFe 2 O 4 composite.…”

“…The Raman spectrum of FNHDNi in Figure 7C exhibits two less intense bands, nearly 2704 and 2975 cm −1 , which can be assigned to the intrinsic CH 2 stretching band directly connected to the amide linkage of L-dopa. 58 Again, the presence of the characteristic peak for the azomethine stretch 59 at 1650 cm −1 clearly suggests the successful amalgamation of L-dopa and complex 1 over the FSWCNHs@NiFe 2 O 4 composite.…”