Functional reorganization of the attentional networks in low-grade glioma patients: A longitudinal study

White matter tractography for neurosurgical planning: A topography-based review of the current state of the art

“…In conjunction with other modern advances (functional MRI, neuronavigation, intraoperative fluorescence guidance, intraoperative MRI), WMT-based surgery is currently recognized as a valuable tool for balancing the trade-off between function preservation and maximized resection in both high grade and low grade gliomas (Barbosa et al, 2016, Charras et al, 2015, Kekhia et al, 2011, Kuhnt et al, 2012, Wu et al, 2007). The importance of understanding the individual patient's white matter configuration during surgical planning comes from the relatively unpredictable nature of fiber/tumor interaction in the context of intra-axial tumors, particularly slowly growing low grade gliomas.…”

“…Sparing these tracts is essential since white matter displays relatively limited functional reorganization possibilities, when compared to the cortex (Yogarajah et al, 2010). White matter tracts also play a crucial part in local then distal functional cortical recruiting (Charras et al, 2015, van Geemen et al, 2014), which not only helps patients compensate for preoperative functional cortex damage but also aids recuperation from possible surgery-inflicted deficits. Accordingly, sparing these important connections is an important prognosis factor not only for the acute postoperative phase, but also for the long term functional surgical outcome.…”

Diffusion Tensor Imaging Shows Corpus Callosum Differences between High‐Grade Gliomas and Metastases

“…A number of recent studies have demonstrated a capacity of the brain for transcallosal interhemispheric transfer of function from a damaged hemisphere to the contralateral side. Such brain plasticity has been described in patients with amputation, stroke, and brain tumors . In patients with brain cancer, there have also been mixed results if tumor volume impacts the degree of contralateral brain reorganization, while improved neurocognitive capabilities have been associated with increased contralateral brain reorganization …”

“…Such brain plasticity has been described in patients with amputation, 11 stroke, [12][13][14] and brain tumors. [15][16][17][18][19][20][21][22][23][24] In patients with brain cancer, there have also been mixed results if tumor volume impacts the degree of contralateral brain reorganization, [20][21][22] while improved neurocognitive capabilities have been associated with increased contralateral brain reorganization. 23,24 In addition to inducing functional activation changes from contralateral brain reorganization, neuropathologies are known to induce structural changes specifically in the CC.…”

“…[15][16][17][18][19][20][21][22][23][24] In patients with brain cancer, there have also been mixed results if tumor volume impacts the degree of contralateral brain reorganization, [20][21][22] while improved neurocognitive capabilities have been associated with increased contralateral brain reorganization. 23,24 In addition to inducing functional activation changes from contralateral brain reorganization, neuropathologies are known to induce structural changes specifically in the CC. Studies using DTI involving patients and healthy controls have shown that the patients had lower FA values in the CC than healthy controls for many conditions including lower limb amputations, 25 stroke, 26 epilepsy, 27 migraines, 28 idiopathic scoliosis, 29 and brain cancer.…”