ä Despite an increasing rate of civilian low-velocity gunshot injuries, there remains a lack of evidence-based treatment standards.ä Most low-velocity gunshot-induced fractures of the extremity can be managed similarly to non-gunshot-induced fractures, with the goals of restoring function and minimizing complications.ä There are a limited number of high-quality studies to support the use of prophylactic antibiotics for nonoperatively treated gunshot wounds.ä Intra-articular retained bullets should be removed, while prophylactic irrigation and debridement for a transarticular bullet is not routinely warranted for infection prevention.ä Much of the literature on low-velocity gunshot wounds is Level-III or IV evidence, warranting the need for higherpowered, randomized, prospective investigations.Gun violence and firearm injuries are serious public health problems in the United States. Civilian gunshot wounds (GSWs) are associated with substantial morbidity, mortality, and socioeconomic consequences. The incidence of nonfatal GSWs continues to increase in the United States, with an estimated 535,150 nonfatal GSWs between 2014 to 2018, increasing approximately 41% over the previous 5 years 1 . GSWs have increased from eighth to sixth among the most common causes of nonfatal violence-related emergency department visits 1 . Nonfatal GSWs disproportionately impact males, members of racial and/or ethnic minorities, and those under the age of 35 years 2 . Urban areas remain the predominant center of injury, with most gun violence concentrated among high-risk populations 3 . These injuries have profound economic impact, with the cost of care in the U.S. exceeding $2.7 billion annually 4 .The military experience has provided the basis for highvelocity GSW management. However, most GSWs presenting to civilian medical facilities are caused by low-velocity handguns 5 . Despite the increasing frequency of civilian GSWs, the management of these injuries is debated 4,[6][7][8][9] . The present review focuses on the current best evidence on the management of low-velocity GSWs to an extremity in the civilian population. GSWs to the spine and high-velocity GSWs are not discussed.
Historical Perspective and BallisticsPrior to the 17th century, bacteria were unknown and infection from GSWs was thought to be secondary to gunpowder poisoning. During that era, standard of care was bullet removal and cautery 10 . Although wartime data have provided foundational principles for the treatment of high-velocity GSWs, there are distinct differences in the management of civilian lowvelocity GSWs. By definition, low-velocity bullets travel <2,000 ft/s (610 m/s) (while high-velocity bullets travel >2,000 ft/s). Bullet properties (mass and shape), travel characteristics (yaw, tumble, and velocity), impact characteristics (pass-through Disclosure: The authors indicated that no external funding was received for any aspect of this work. On the Disclosure of Potential Conflicts of Interest forms, which are provided with the online version of the article...