Functional nutraceuticals: past, present, and future

Kaur, Khushwinder

doi:10.1016/b978-0-12-804305-9.00002-6

Cited by 7 publications

(4 citation statements)

References 83 publications

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“…These by-products are an excellent source of essential oil and bioactive compounds such as flavones and polyphenols. The trend for the use of fruit waste to extract valuable compounds and their useindeveloping functional and nutraceutical food products has been increased [4]. Citrus peels contain the highest amount of polymethoxylated flavones such as nobiletin and tangeretin, as compared to other parts [5,6].…”

Section: Introductionmentioning

confidence: 99%

Effect of Ultrasound-Assisted Pretreatment on Extraction Efficiency of Essential Oil and Bioactive Compounds from Citrus Waste By-Products

et al. 2021

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Waste or by-product use is in focus for reducing the environmental threat and acquiring wealth out of waste. The current study aim was to investigate the effects of ultrasound pretreatment on the extraction of bioactive compounds and composition of essential oils extracted from citrus waste. The response surface methodology (RSM) was used to optimize higher yield extraction parameters. Pretreatment of ultrasound-assisted extraction recovered 33% enhanced yield with reduced time and was economical as compared to conventional hydro-distilled process. The functional quality of essential oil was determined using FTIR and GC-MS. Antioxidants from citrus peel and pulp/pomace were extracted and analyzed by spectroscopic techniques. The quantification of bioactive compounds from citrus waste was performed using high performance liquid chromatography (HPLC). Mass transfer rate of antioxidants from peel and pomace were 30% increased as a result of ultrasound-assisted treatment. The significantly (p ≤ 0.05) higher TPC (735.54 mg/100 g) and antioxidant activity (44.26%) was recorded in Citrus sinensis Pulp and peel respectively. The bioactive compounds such as hesperidin (31.52 mg/100 g) was significantly higher in (p ≤ 0.05) in Citrus sinensis pulnd extract. Vanillin was found 1.21 mg/100 g in peel extract of citrus fruit, moreover vanillin was not detected in pulp extract. Myrecitin was not detected in both the samples. The bioactive natural compounds extracted from citrus peel can be used in food and pharma sector as natural anti-oxidantcompounds.

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Section: Introductionmentioning

confidence: 99%

Effect of Ultrasound-Assisted Pretreatment on Extraction Efficiency of Essential Oil and Bioactive Compounds from Citrus Waste By-Products

et al. 2021

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“…In recent years, the attention of researchers has been addressed to the study and the use of medicinal plants in clinical practice [5], thanks to their special antioxidant properties, cell cycle inhibition, promotion of tissue regeneration, and inhibition of acute inflammation [6, 7]. The role of free radical reactions, in fact, is well known for some pathologies.…”

Section: Introductionmentioning

confidence: 99%

Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions

Cruciani

Santaniello

Fadda

et al. 2019

BioMed Research International

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Nutraceuticals present in food are molecules able to exert biological activity for the prevention and treatment of various diseases, in form of pharmaceutical preparations, such as capsules, cream, or pills. Myrtus communis L. is a spontaneous Mediterranean evergreen shrub, widely known for the liqueur obtained from its berries rich in phytochemicals such as tannins and flavonoids. In the present study, we aimed to evaluate the properties of myrtle byproducts, residual of the industrial liqueur processing, in Adipose-derived stem cells (ADSCs) induced at oxidative stress by in vitro H2O2 treatment. Cells were exposed for 12-24 and 48h at treatment with extracts and then senescence-induced. ROS production was then determined. The real-time PCR was performed to evaluate the expression of inflammatory cytokines and sirtuin-dependent epigenetic changes, as well the modifications in terms of stem cell pluripotency. The β-galactosidase assay was conducted to analyze stem cell senescence after treatment. Our results show that industrial myrtle byproducts retain a high antioxidant and antisenescence activity, protecting cells from oxidative stress damages. The results obtained suggest that residues from myrtle liqueur production could be used as resource in formulation of food supplements or pharmaceutical preparations with antioxidant, antiaging, and anti-inflammatory activity.

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“…However, there are still some discrepancies to classify them or to correctly define them as nutraceuticals because of different regulations in which such kind of compounds can only be registered as functional foods and nutritional or dietary supplements [171]. Nowadays, it is largely accepted that the nutraceutical concept involves formulations that contain certain pure active ingredients or substances isolated from food sources, herbal products and dietary supplements, which have a proven therapeutic effect when they are regularly consumed [28,172,173]. In other words, nutraceuticals are pharmaceutical formulations that by their periodic consumption exert both nutritional and therapeutic effects.…”

Section: Advances In Natural Antioxidant Formulations: a Potential To...mentioning

confidence: 99%

Antioxidants in Plants: A Valorization Potential Emphasizing the Need for the Conservation of Plant Biodiversity in Cuba

et al. 2020

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Plants are phytochemical hubs containing antioxidants, essential for normal plant functioning and adaptation to environmental cues and delivering beneficial properties for human health. Therefore, knowledge on the antioxidant potential of different plant species and their nutraceutical and pharmaceutical properties is of utmost importance. Exploring this scientific research field provides fundamental clues on (1) plant stress responses and their adaptive evolution to harsh environmental conditions and (2) (new) natural antioxidants with a functional versatility to prevent and treat human pathologies. These natural antioxidants can be valorized via plant-derived foods and products. Cuba contains an enormously rich plant biodiversity harboring a great antioxidant potential. Besides opening new avenues for the implementation of sustainable agroecological practices in crop production, it will also contribute to new strategies to preserve plant biodiversity and simultaneously improve nature management policies in Cuba. This review provides an overview on the beneficial properties of antioxidants for plant protection and human health and is directed to the valorization of these plant antioxidants, emphasizing the need for biodiversity conservation.

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Functional nutraceuticals: past, present, and future

Cited by 7 publications

References 83 publications

Effect of Ultrasound-Assisted Pretreatment on Extraction Efficiency of Essential Oil and Bioactive Compounds from Citrus Waste By-Products

Effect of Ultrasound-Assisted Pretreatment on Extraction Efficiency of Essential Oil and Bioactive Compounds from Citrus Waste By-Products

Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions

Antioxidants in Plants: A Valorization Potential Emphasizing the Need for the Conservation of Plant Biodiversity in Cuba

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