Functional Hepatoma Demonstrated With Rose Bengal Scanning

Shoop, Jon D.

doi:10.2214/ajr.107.1.51

Cited by 21 publications

(5 citation statements)

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“…This has been true whether the isotope was concentrated in the parenchymal cell or the RES. However, as exemplified by this and another recent report (Shoop, 1969), some lesions may hyperconcentrate the radioactivity.…”

Section: Discussionsupporting

confidence: 51%

“…Because the radioisotopic agent used was of the type which concentrates on the RES, a tumor containing this tissue was suspected and was found a t surgery. Previous reports indicate t h a t most hemangiomas appear as areas of decreased radioactivity (Kreel et al, 1968;O'Mara, 1968;Shoop, 1969). Just the opposite might be expected t o occur since cells with phagocytizing capacity line the sinusoids and the blood vessels of hemangiomas.…”

Section: Discussionmentioning

confidence: 92%

“…Primary hepatic tumors, both benign and malignant, metastatic tumors, abscesses, and cysts are similar in appearance on scintiscan, regardless of the radioisotopic agent used (Johnson and Grossman, 1965 ;Kreel etal., 1968;O'Mara, 1968;Wagner et al, 1961 ;Wagner and Mishkin, 1968). Recently, a case was reported wherein a well-differentiated hepatic cell carcinoma was seen t o concentrate rose bengal 13'1 t o a greater extent than the surrounding normal liver on scintiscan (Shoop, 1969). In this report, a hepatic lesion is reported which presented as an area of increased activity on a colloidal gold-198 scan.…”

Section: Introductionmentioning

confidence: 82%

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‘Hot’ hepatic hemangioma: A unique radiocolloid‐concentrating liver scan lesion

Volpe

Johnston

1970

Journal of Surgical Oncology

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The unique case is reported of a liver hemangioma which appeared on scintiscan as an area of increased concentration of radiogold—‐a ‘hot’ lesion. The scintiscan appearance described is explained by the presence of increased amounts of reticuloendothelial tissue in the tumor over that in the surrounding normal tissue. The usual scan picture of liver hemangioma is that of a ‘cold’ lesion.

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Section: Discussionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 82%

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‘Hot’ hepatic hemangioma: A unique radiocolloid‐concentrating liver scan lesion

Volpe

Johnston

1970

Journal of Surgical Oncology

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“…The observations of uptake of hepatobiliary radiopharmaceuticals by hepatoma (Belfer et al 1979), hepatocellular carcinoma (Shoop 1969;Lee and Shapiro 1983) and hepatoblastoma (De Kraker etal. 1989) led De to administer a therapeutic dose of 1.85 GBq (50 mCi) 13~I Rose Bengal to a 7-month-old child with hepatoblastoma, which was progressive after radiotherapy and chemotherapy and which demonstrated considerable uptake and retention of ~3aI Rose Bengal (tumour uptake 28.7% of the dose of 24 h).…”

Section: /Rose Bengalmentioning

confidence: 99%

Radionuclide therapy revisited

Hoefnagel

1991

Eur J Nucl Med

123

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Apart from its use in endocrinology and rheumatology, therapeutic nuclear medicine is developing rapidly as an additional treatment modality in oncology. Many different specific tumour-seeking radiopharmaceuticals are being applied both for diagnostic scintigraphy and treatment, using multiple routes and mechanisms to target radionuclides at tumours. After a brief introduction of some basic principles of radionuclide targeting, the therapeutic radiopharmaceuticals available are reviewed according to the accumulation site in relation to the cell nucleus; the results of their current clinical use for therapy are also reviewed. The response observed to a number of these applications, the non-invasiveness of the procedure and the relative lack of toxicity and late effects in comparison with chemotherapy and external beam radiotherapy make radionuclide therapy an attractive and realistic alternative in the management of malignant disease, as well as in the treatment of a few benign disorders.

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“…1,2 The cases where liver tumors could be delineated, however, are very rare. 3 In 1985, the concentration of Tc-99m(Sn)-Npyridoxyl-5-methyltryptophan (99aTc-PMT) for detecting hepatocellular carcinomas was reported.…”

Section: Since Introduced Bymentioning

confidence: 99%

Small hepatocellular carcinoma visualized with Technetium-99m(Sn)-N-pyridoxyl-5-methyltryptophan

et al. 1987

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We report a case of small hepatocellular carcinoma depicted by 99mTc-PMT scintigraphy. On the X-ray computed tomogram there was no visualization of a SOL in the liver. Ultrasonography showed a hyperechoic mass of less than 2 cm in diameter in the left lateral segment of the liver. In the image obtained at 3 hr after 99mTc-PMT injection there was an area of markedly increased activity. When the surgery, left lateral segmentectomy of the liver, was performed more than 2 months later, the tumor had enlarged to 2.5 x 2.0 x 1.5 cm in size. 99mTc-PMT may prove to be useful for scintigraphic localization of small hepatocellular carcinoma.

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Functional Hepatoma Demonstrated With Rose Bengal Scanning

Cited by 21 publications

References 0 publications

‘Hot’ hepatic hemangioma: A unique radiocolloid‐concentrating liver scan lesion

‘Hot’ hepatic hemangioma: A unique radiocolloid‐concentrating liver scan lesion

Radionuclide therapy revisited

Small hepatocellular carcinoma visualized with Technetium-99m(Sn)-N-pyridoxyl-5-methyltryptophan

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