Functional Cosmetic Characteristics of Momordica charantia Fruit Extract

Abstract

− In this research, water and ethanol extract of Momordica charantia shells, fruits and seeds were tested to see possibility as natural functional cosmetic agent. Water and ethanol extract showed 69.45 mg/g and 70.87 mg/g polyphenol concentration, respectively. Momordica charantia water and ethanol extracts did not indicate cell toxicity up to 1,000 µg/mL concentration in MTT assay. Tyrosinase inhibition effects of water and ethanol extract were lower than arbutin, however, ethanol extract showed better DOPA oxidation inhibition effect than arbutin. Elastase inhibition effects of ethanol extract displayed similar efficacy with adenosine at higher concentrations. Solution formulations (5% extract) were stable for 28 days in both extracts, however, lotion formulation (1% extract) showed considerable variation in viscosity whereas ethanol extraction indicated relative stability. In conclusion, water and ethanol extract of Momordica charantia shells, fruits and seeds indicated strong possibility for whitening and antiwrinkle functional cosmetic ingredient.

Variation on Charantin Contents of Various Organs and Harvest Seasons in Bitter Gourd

“…중국, 태국 등의 아시아지역에서는 과실 뿐 아니라 잎, 줄기 등을 식용 또는 가공용으로 이용하고 있다 (Kubola and Siriamornpun, 2008). 국내에서는 미숙과만을 식용대상으로 생과 및 가공품이 판매되고 있으며, 과실의 열수 및 에탄올 추출물에 대해 미백 또는 주름개선 효과검토 등 기능성 화장품 소재로서의 가능성을 모색하고 있다 (Kim et al, 2015). 식품의약품안전처에서는 여 주의 열매, 잎, 생장점은 식품원료 사용 가능부위로 분류하고 있고, 씨, 덩이줄기, 뿌리는 식용 불가능한 부위로 구분함에 따라 일부 잎의 가공품도 유통이 어려운 실정이다.…”