Functional connectivity reveals load dependent neural systems underlying encoding and maintenance in verbal working memory

Woodward, Todd S.; Cairo, Tara A.; Ruff, Christian C.; Takane, Yoshio; Hunter, Michael A.; Ngan, Elton T.C.

doi:10.1016/j.neuroscience.2005.05.043

Cited by 111 publications

(97 citation statements)

References 32 publications

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“…This view stands in contrast to the interpretations of previous fMRI findings in which PPC activations were associated with maintenance of visual information in WM (Leung, Oh, Ferri, & Yi, 2007;Moore, Cohen, & Ranganath, 2006;Todd & Marois, 2004;Woodward et al, 2006;Xu & Chun, 2006). One explanation for this is that activity during the WM maintenance period reflects an attentional tagging process important for memory retrieval.…”

Section: Discussioncontrasting

confidence: 93%

The right parietal lobe is critical for visual working memory

Berryhill

Olson

2008

Neuropsychologia

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Neuroimaging evidence suggests that the parietal lobe has an important role in memory retrieval, yet neuropsychology is largely silent on this topic. Recently, we reported that unilateral parietal lobe damage impairs various forms of visual working memory when tested by old/new recognition. Here, we investigate whether parietal lobe working memory deficits are linked to problems at retrieval. We tested two patients with bilateral parietal lobe damage in a series of visual working memory tasks that probed recall and old/new recognition. Stimuli were presented sequentially and several stimulus categories were tested. The results of these experiments show that parietal lobe damage disproportionately impairs old/new recognition as compared to cued recall across stimulus categories. The observed performance dissociation suggests that the posterior parietal lobe plays a particularly vital role in working memory retrieval.

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Section: Discussioncontrasting

confidence: 93%

The right parietal lobe is critical for visual working memory

Berryhill

Olson

2008

Neuropsychologia

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“…Activated areas were similar to previous fMRI findings using the Sternberg task to examine WM load-related activation during encoding and maintenance separately (e.g. Cairo, Liddle, Woodward, & Ngan, 2004;Veltman, Rombouts, & Dolan, 2003;Woodward et al, 2006). Load-dependent encoding phase activation was found in the DMPFC, right DLPFC and bilateral parietal cortices.…”

Section: Working Memory Task Fmri Resultssupporting

confidence: 85%

Working memory in middle-aged males: Age-related brain activation changes and cognitive fatigue effects

Klaassen

Evers

Groot

et al. 2014

Biological Psychology

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“…Previous fMRI studies showed a neural correlate for the capacity limitation of VSTM in frontal and parietal cortex (Linden et al, 2003;Todd and Marois, 2004), in which brain activity increased monotonically with higher memory loads until the capacity limit was reached. Furthermore, retention of higher memory loads may be associated with increased functional coupling between these brain areas (Honey et al, 2002;Woodward et al, 2006). Thus, higher memory loads may require more neural resources for memory retention, which may leave limited resources available to protect against interfering signals.…”

Section: Discussionmentioning

confidence: 99%

Topographic Contribution of Early Visual Cortex to Short-Term Memory Consolidation: A Transcranial Magnetic Stimulation Study

Ven¹,

Jacobs²,

Sack³

2012

J. Neurosci.

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The neural correlates for retention of visual information in visual short-term memory are considered separate from those of sensory encoding. However, recent findings suggest that sensory areas may play a role also in short-term memory. We investigated the functional relevance, spatial specificity, and temporal characteristics of human early visual cortex in the consolidation of capacity-limited topographic visual memory using transcranial magnetic stimulation (TMS). Topographically specific TMS pulses were delivered over lateralized occipital cortex at 100, 200, or 400 ms into the retention phase of a modified change detection task with low or high memory loads. For the high but not the low memory load, we found decreased memory performance for memory trials in the visual field contralateral, but not ipsilateral to the side of TMS, when pulses were delivered at 200 ms into the retention interval. A behavioral version of the TMS experiment, in which a distractor stimulus (memory mask) replaced the TMS pulses, further corroborated these findings. Our findings suggest that retinotopic visual cortex contributes to the short-term consolidation of topographic visual memory during early stages of the retention of visual information. Further, TMS-induced interference decreased the strength (amplitude) of the memory representation, which most strongly affected the high memory load trials.

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Functional connectivity reveals load dependent neural systems underlying encoding and maintenance in verbal working memory

Cited by 111 publications

References 32 publications

The right parietal lobe is critical for visual working memory

The right parietal lobe is critical for visual working memory

Working memory in middle-aged males: Age-related brain activation changes and cognitive fatigue effects

Topographic Contribution of Early Visual Cortex to Short-Term Memory Consolidation: A Transcranial Magnetic Stimulation Study

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