Function of Nuclear Pore Complexes in Regulation of Plant Defense Signaling

Abstract

In eukaryotes, the nucleus is the regulatory center of cytogenetics and metabolism, and it is critical for fundamental biological processes, including DNA replication and transcription, protein synthesis, and biological macromolecule transportation. The eukaryotic nucleus is surrounded by a lipid bilayer called the nuclear envelope (NE), which creates a microenvironment for sophisticated cellular processes. The NE is perforated by the nuclear pore complex (NPC), which is the channel for biological macromolecule bi-directional transport between the nucleus and cytoplasm. It is well known that NPC is the spatial designer of the genome and the manager of genomic function. Moreover, the NPC is considered to be a platform for the continual adaptation and evolution of eukaryotes. So far, a number of nucleoporins required for plant-defense processes have been identified. Here, we first provide an overview of NPC organization in plants, and then discuss recent findings in the plant NPC to elaborate on and dissect the distinct defensive functions of different NPC subcomponents in plant immune defense, growth and development, hormone signaling, and temperature response. Nucleoporins located in different components of NPC have their unique functions, and the link between the NPC and nucleocytoplasmic trafficking promotes crosstalk of different defense signals in plants. It is necessary to explore appropriate components of the NPC as potential targets for the breeding of high-quality and broad spectrum resistance crop varieties.

Transcriptome profiling of high and low somatic embryogenesis rate of oil palm (Elaeis guineensis Jacq. var. Tenera)

“…The nuclear pore complex (NPC) mutant was reported to inhibit the somatic embryo development in Arabidopsis. It was because the signaling pathway of some phytohormones was sensitive to the interference of NPC (Wu et al, 2022). The function of uncharacterized LOC105049880 gene in addition to being related to somatic embryogenesis is not well characterized.…”

Nuclear envelope dynamics in connection to chromatin remodeling

“…Additionally, mTOR is also able to sense interruptions between chromatin and the NE, since lamin deficiency leads to mTOR hyperactivation (Chiarini et al, 2019;Ramos et al, 2012). In plants, TOR has recently been found to be involved in H3K27me3 deposition and PRC2-mediated silencing of genes involved in development and stress responses (Dong et al, 2023;Ye Tamura & Hara-Nishimura, 2011; Barneche & Baroux, 2017;Bi et al, 2017;Gozalo et al, 2020;Goto et al, 2021;Wu et al, 2022;Tang, Dong, et al, 2022;Tang, Ho, et al, 2022…”