The objective of this study was to evaluate the phytochemical, antimicrobial, and insecticidal properties of tannins derived from Cydonia oblonga fruit.Qualitative and quantitative methods were used for the determination of the phytochemicals of Cydonia oblonga fruits. The tannins of this fruit were extracted using solvents and salts, and their antimicrobial activity against S. aureus ATCC 25923 and E.coli ATCC 25322 and C.albicans was investigated.The lethal effect of tannins extract was evaluated on Tribolium confusum under controlled laboratory conditions (at temperature 28 ± 2°C, relative humidity 75 ± 5%, and photoperiod of 16:8).The obtained results showed very interesting levels of tannins extraction (9.66%, 7.33%) using solvents and salts, respectively. The obtained tannins exerted no antimicrobial activity for the tested strains.On the other hand, all doses (50 μl, 100 μl, and 200 μl) of tannins tested on Tribolium confusum adults by the inhalation method showed a bioinsecticidal effect with an LD50 of 109.64 μl of tannin extract. Cydonia oblonga fruit can be an alternative for the development of natural drugs and insecticides with an important role in the fight against parasites.