2006
DOI: 10.1053/j.ajkd.2005.11.033
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Fulminant Pulmonary Calciphylaxis and Metastatic Calcification Causing Acute Respiratory Failure in a Uremic Patient

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Cited by 33 publications
(31 citation statements)
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“…Systemic symptoms secondary to vascular and extravascular calcification of internal organs and soft tissues may also occur. Patients may develop cardiac valve or electrical conduction dysfunction, myocardial, pulmonary, or cerebrovascular infarction (80,81), myositis, muscle weakness, and bowel infarction (70,80). Histologically, calcification of small-and medium-sized blood vessels is seen in the dermis and subcutaneous tissue, although this finding can be quite subtle and may be missed.…”
Section: Metastatic Calcificationmentioning
confidence: 99%
See 1 more Smart Citation
“…Systemic symptoms secondary to vascular and extravascular calcification of internal organs and soft tissues may also occur. Patients may develop cardiac valve or electrical conduction dysfunction, myocardial, pulmonary, or cerebrovascular infarction (80,81), myositis, muscle weakness, and bowel infarction (70,80). Histologically, calcification of small-and medium-sized blood vessels is seen in the dermis and subcutaneous tissue, although this finding can be quite subtle and may be missed.…”
Section: Metastatic Calcificationmentioning
confidence: 99%
“…Computed tomography can also identify calcified arterioles in the soft tissues as well as calcification of the viscera. These findings and other radiographic findings seen in CUA are summarized in Table 5 (81)(82)(83).…”
Section: Metastatic Calcificationmentioning
confidence: 99%
“…La vitamina D utilizada frecuentemente aumenta la absorción intestinal de calcio y fósforo y las sales de calcio utilizadas como quelantes también facilitarían a la calcificación metastásica y vascular 7,32 . También es posible que el contenido elevado de calcio en las soluciones de HD favorezca la calcificación tisular 18 . En este paciente, con una buena función del injerto renal, no es claro el mecanismo por el cual desarrolló CPM.…”
Section: Discussionunclassified
“…La evolución clínica de las CPM habitualmente es benigna y a menudo asintomática. Otras veces existe tos no productiva y disnea de esfuerzo, ocasionalmente puede seguir un curso fulminante y fatal 9,14,17 o asociarse a calcifilaxis y necrosis pulmonar 18 . Las CPM se han observado también en pacientes con hiperparatiroidismo primario y secundario, hipercalcemias de otras causas, terapia endovenosa con calcio, mieloma múltiple, leucemias, sarcoidosis, intoxicación por vitamina D, osteolisis masiva por metástasis, síndrome de leche-alcalinos, enfermedad de Paget , neoplasia endocrina múltiple 9,19-21 y en trasplantados renales (TxR) con injertos disfuncionantes 4,7,14,16,17,22,23 .…”
unclassified
“…Patients often succumb to sepsis, and, less frequently, organ failure, within several months of diagnosis. 18 Early diagnosis allows implementation of a multidisciplinary approach to treatment with the goal of improving the quality of life. 16,19 …”
mentioning
confidence: 99%