“…FHF typi cally occurs within 8 weeks of the onset of symptoms of liver disease [1], This condition also implies that if survival occurs, hepatocel lular function usually returns to normal with removal of the offending insult [1]. FHF has numerous etiologies including viral hepatitis, various drugs and toxins, Reye's syndrome, Budd-Chiari syndrome, acute fatty liver of pregnancy, Wilson's disease, and prolonged episodes of circulatory insult [1,2], Our pa tient initially had negative viral markers for hepatitis A and B with no risk factors for hep atitis C infection. The possibility of a non-A, non-B, non-C etiology causing fulminant he patic failure, as has been previously recog nized, was a consideration in his case [3], Prolonged ischemia has been clearly de scribed in the literature as an etiology of FHF [4][5][6][7][8], However, we feel our case is unique in that all other descriptions have involved pa tients with a history of known or suspected cardiac insufficiency, whereas our patient had been a well-conditioned athlete without a his tory or clinical evidence of heart disease on presentation.…”