Fully implantable batteryless soft platforms with printed nanomaterial-based arterial stiffness sensors for wireless continuous monitoring of restenosis in real time

Herbert, Robert; Elsisy, Moataz; Rigo, Bruno; Lim, Hyo‐Ryoung; Kim, Hyeonseok; Choi, Chanyeong; Kim, Seungil; Ye, Sang‐Ho; Wagner, William R.; Chun, Youngjae; Yeo, Woon‐Hong

doi:10.1016/j.nantod.2022.101557

Cited by 13 publications

(19 citation statements)

References 70 publications

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“…Using inductive coupling with an external antenna, arterial pressure, blood flow, and pulse rate were monitored continuously without batteries or additional implanted circuits. Similarly, an arterial stiffness sensor was reported by Herbert et al In the electronic stent, nanomembrane strain sensors monitored restenosis, as shown in Figure 8N 245 . The ex vivo experiments performed for arterial wall stiffening (0%, 60%, 75%, and 90%) demonstrated cardiovascular health monitoring and prediction of the risk of cardiovascular failure.…”

Section: Representative Examples Of Bioelectronic Systemssupporting

confidence: 54%

“…Similarly, an arterial stiffness sensor was reported by Herbert et al In the electronic stent, nanomembrane strain sensors monitored restenosis, as shown in Figure 8N. 245 The ex vivo experiments performed for arterial wall stiffening (0%, 60%, 75%, and 90%) demonstrated cardiovascular health monitoring and prediction of the risk of cardiovascular failure.…”

Section: Bioelectronic Systems For Heart and Blood Vesselsmentioning

confidence: 56%

“…(M) Reproduced with permission: 2022, American Association for the Advancement of Science 244 . (N) Reproduced with permission: 2022, Elsevier 245 …”

Section: Representative Examples Of Bioelectronic Systemsmentioning

confidence: 99%

“…244 (N) Reproduced with permission: 2022, Elsevier. 245 As depicted in Figure 8A, Liu et al reported an intrinsically stretchable and elastic electrode array implanted in vivo for electrophysiological mapping of the heart of a patient with atrial fibrillation. 234 The stretchable electrode array was fabricated with Au and poly (3,4-ethylenedioxythiophene): poly(styrene sulfonate) (PEDOT:PSS) electrodes with a fluorinated elastomer on the bottom PDMS layer and a perfluoropolyether (PFPE)-dimethylacetamide (DMA) passivation layer before implantation.…”

Section: Bioelectronic Systems For Heart and Blood Vesselsmentioning

confidence: 99%

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Wearable and implantable bioelectronics as eco‐friendly and patient‐friendly integrated nanoarchitectonics for next‐generation smart healthcare technology

Kim

Baek

Sluyter

et al. 2023

EcoMat

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Since the beginning of human history, the demand for effective healthcare systems for diagnosis and treatment of health problems has grown steadily. However, traditional centralized healthcare requires hospital visits, making in‐time and long‐term healthcare challenging. Bioelectronics has shown potential in patient‐friendly healthcare owing to the rapid advances in diverse fields of biology and electronics. In particular, wearable and implantable bioelectronics have emerged as an alternative or adjunct to conventional healthcare. To develop into next‐generation healthcare systems, however, custom designs for biological targets with a deepened understanding of the intrinsic features of the target are essential. In addition, bioelectronic systems must be designed eco‐friendly for sustainable healthcare. In this review, bioelectronics as eco‐friendly and patient‐friendly integrated nanoarchitectonics as next‐generation smart healthcare technology are described. For an in‐depth understanding of biological targets and guidelines for target‐tailored design, we discuss target‐specific considerations and relevant key parameters of bioelectronic systems with the representative examples.

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Section: Representative Examples Of Bioelectronic Systemssupporting

confidence: 54%

Section: Bioelectronic Systems For Heart and Blood Vesselsmentioning

confidence: 56%

“…(M) Reproduced with permission: 2022, American Association for the Advancement of Science 244 . (N) Reproduced with permission: 2022, Elsevier 245 …”

Section: Representative Examples Of Bioelectronic Systemsmentioning

confidence: 99%

Section: Bioelectronic Systems For Heart and Blood Vesselsmentioning

confidence: 99%

See 2 more Smart Citations

Wearable and implantable bioelectronics as eco‐friendly and patient‐friendly integrated nanoarchitectonics for next‐generation smart healthcare technology

Kim

Baek

Sluyter

et al. 2023

EcoMat

View full text Add to dashboard Cite

show abstract

“…Implantable biosensors can continuously monitor important physiological signals and biochemical indicators in real time and in situ. − With their use, it is convenient for the medical staff to manage the diseases and improve the nursing conditions of patients. However, most existing implantable sensors must be removed or replaced by invasive and complex surgery at the end of their useful lives − since they can not only impose a heavy financial burden but also cause physical and mental injuries to patients.…”

Section: Introductionmentioning

confidence: 99%

Bioresorbable Pressure Sensor and Its Applications in Abnormal Respiratory Event Identification

Liu

Deng

2023

ACS Appl. Electron. Mater.

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Bioresorbable electronics that can be absorbed and become a part of the organism after their service life are becoming a trend to avoid secondary invasive surgery. However, the sustainable and secure supply of energy for biosensors is a significant challenge. Here, a bioresorbable pressure sensor (BPS) based on a triboelectric nanogenerator is reported. The BPS based on the triboelectric nanogenerator can directly convert ambient pressure changes into electrical signals. It offers excellent sensitivity (22.61 mV/mmHg), linearity (R 2 = 0.99), and good durability (850,000 cycles). The bioresorbable materials of poly(lactic acid)/ chitosan/sodium alginate in the BPS show great biocompatibility and can achieve 99.99% sterilization for both Gram-positive bacteria and Gram-negative bacteria. In addition, the device can successfully identify an abnormal respiratory event in small animals and will be completely degraded after 21 days. The BPS only employs medical materials used commonly in FDA-approved implants, which is crucial for the biosafety of bioresorbable devices. Triboelectric devices are expected to be applied in the clinic as bioresorbable electronics.

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A Review of Recent Advancements in Sensor‐Integrated Medical Tools

Park,

Seo,

Jeong

et al. 2024

Advanced Science

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A medical tool is a general instrument intended for use in the prevention, diagnosis, and treatment of diseases in humans or other animals. Nowadays, sensors are widely employed in medical tools to analyze or quantify disease‐related parameters for the diagnosis and monitoring of patients’ diseases. Recent explosive advancements in sensor technologies have extended the integration and application of sensors in medical tools by providing more versatile in vivo sensing capabilities. These unique sensing capabilities, especially for medical tools for surgery or medical treatment, are getting more attention owing to the rapid growth of minimally invasive surgery. In this review, recent advancements in sensor‐integrated medical tools are presented, and their necessity, use, and examples are comprehensively introduced. Specifically, medical tools often utilized for medical surgery or treatment, for example, medical needles, catheters, robotic surgery, sutures, endoscopes, and tubes, are covered, and in‐depth discussions about the working mechanism used for each sensor‐integrated medical tool are provided.

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Fully implantable batteryless soft platforms with printed nanomaterial-based arterial stiffness sensors for wireless continuous monitoring of restenosis in real time

Cited by 13 publications

References 70 publications

Wearable and implantable bioelectronics as eco‐friendly and patient‐friendly integrated nanoarchitectonics for next‐generation smart healthcare technology

Wearable and implantable bioelectronics as eco‐friendly and patient‐friendly integrated nanoarchitectonics for next‐generation smart healthcare technology

Bioresorbable Pressure Sensor and Its Applications in Abnormal Respiratory Event Identification

A Review of Recent Advancements in Sensor‐Integrated Medical Tools

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