Fullerenes in Electrochemical Catalytic and Affinity Biosensing: A Review

Yáñez‐Sedeño, Paloma; Campuzano, Susana; Pingarrón, José M.

doi:10.3390/c3030021

Cited by 33 publications

(22 citation statements)

References 41 publications

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“…Fullerene-based nanomaterials have been exploited for biomedical application, and different studies have revealed their biocompatibility with living organisms. It has been used as a bioreceptor as well as a biosensor and also exploited in biomedical engineering, and it has been reported to be biocompatible with living systems [65–69]. The fullerene is a nontoxic material which can be exploited for filtration, adsorbents, and membrane stuff for environmental and water treatment applications.…”

Section: Classification Of Carbon Nanomaterials Based On Their Dimensmentioning

confidence: 99%

Carbon Nanomaterials for the Treatment of Heavy Metal-Contaminated Water and Environmental Remediation

2019

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Nanotechnology is an advanced field of science having the ability to solve the variety of environmental challenges by controlling the size and shape of the materials at a nanoscale. Carbon nanomaterials are unique because of their nontoxic nature, high surface area, easier biodegradation, and particularly useful environmental remediation. Heavy metal contamination in water is a major problem and poses a great risk to human health. Carbon nanomaterials are getting more and more attention due to their superior physicochemical properties that can be exploited for advanced treatment of heavy metal-contaminated water. Carbon nanomaterials namely carbon nanotubes, fullerenes, graphene, graphene oxide, and activated carbon have great potential for removal of heavy metals from water because of their large surface area, nanoscale size, and availability of different functionalities and they are easier to be chemically modified and recycled. In this article, we have reviewed the recent advancements in the applications of these carbon nanomaterials in the treatment of heavy metal-contaminated water and have also highlighted their application in environmental remediation. Toxicological aspects of carbon-based nanomaterials have also been discussed.

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Section: Classification Of Carbon Nanomaterials Based On Their Dimensmentioning

confidence: 99%

Carbon Nanomaterials for the Treatment of Heavy Metal-Contaminated Water and Environmental Remediation

2019

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“…A broad spectrum of compounds that find applications in healthcare diagnosis and POC analysis of diseases can be detected with such biosensor materials [22]. Carbon allotrope-based nanomaterials consisting of fullerenes, [23,24,25,26,27] nanotubes (CNT) [28,29,30,31,32,33], films of graphene and its derivatives [34,35,36,37], quantum dots [38,39,40,41], and nanodiamonds [42,43,44,45,46,47] play a substantial role in recent advancements in the biosensor domain. In addition to greater sensitivity and novel mechanisms, such sensors offer a higher spatial resolution in case of localised detection along with real-time and label-free non-destructive sensing.…”

Section: Carbon Allotrope-based Nanomaterials Applications In Healtmentioning

confidence: 99%

Nanomaterials for Healthcare Biosensing Applications

Pirzada

Altıntaş

2019

Sensors

171

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In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field. Nanomaterials introduce versatility to the sensing platforms and may even allow mobility between different detection mechanisms. The prospect of a combination of different nanomaterials allows an exploitation of their synergistic additive and novel properties for sensor development. This paper covers more than 290 research works since 2015, elaborating the diverse roles played by various nanomaterials in the biosensing field. Hence, we provide a comprehensive review of the healthcare sensing applications of nanomaterials, covering carbon allotrope-based, inorganic, and organic nanomaterials. These sensing systems are able to detect a wide variety of clinically relevant molecules, like nucleic acids, viruses, bacteria, cancer antigens, pharmaceuticals and narcotic drugs, toxins, contaminants, as well as entire cells in various sensing media, ranging from buffers to more complex environments such as urine, blood or sputum. Thus, the latest advancements reviewed in this paper hold tremendous potential for the application of nanomaterials in the early screening of diseases and point-of-care testing.

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“…The effectiveness of enzymatic biosensors is determined by the achievement of an efficient electron transport between redox proteins and electrodes. Due to their complex structures and the deeply buried ligand binding sites of proteins, it is a challenge to achieve direct electron transfer between the redox proteins and the electrode surface [ 129 ]. In addition, redox proteins become irreversibly denatured when adsorbed on the electrode surface [ 119 ].…”

Section: Fullerenes For Electrochemical Biosensorsmentioning

confidence: 99%

Carbon Nanomaterials as Versatile Platforms for Biosensing Applications

et al. 2020

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A biosensor is defined as a measuring system that includes a biological receptor unit with distinctive specificities toward target analytes. Such analytes include a wide range of biological origins such as DNAs of bacteria or viruses, or proteins generated from an immune system of infected or contaminated living organisms. They further include simple molecules such as glucose, ions, and vitamins. One of the major challenges in biosensor development is achieving efficient signal capture of biological recognition-transduction events. Carbon nanomaterials (CNs) are promising candidates to improve the sensitivity of biosensors while attaining low detection limits owing to their capability of immobilizing large quantities of bioreceptor units at a reduced volume, and they can also act as a transduction element. In addition, CNs can be adapted to functionalization and conjugation with organic compounds or metallic nanoparticles; the creation of surface functional groups offers new properties (e.g., physical, chemical, mechanical, electrical, and optical properties) to the nanomaterials. Because of these intriguing features, CNs have been extensively employed in biosensor applications. In particular, carbon nanotubes (CNTs), nanodiamonds, graphene, and fullerenes serve as scaffolds for the immobilization of biomolecules at their surface and are also used as transducers for the conversion of signals associated with the recognition of biological analytes. Herein, we provide a comprehensive review on the synthesis of CNs and their potential application to biosensors. In addition, we discuss the efforts to improve the mechanical and electrical properties of biosensors by combining different CNs.

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Fullerenes in Electrochemical Catalytic and Affinity Biosensing: A Review

Cited by 33 publications

References 41 publications

Carbon Nanomaterials for the Treatment of Heavy Metal-Contaminated Water and Environmental Remediation

Carbon Nanomaterials for the Treatment of Heavy Metal-Contaminated Water and Environmental Remediation

Nanomaterials for Healthcare Biosensing Applications

Carbon Nanomaterials as Versatile Platforms for Biosensing Applications

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