Fullerene-PAMAM(G5) composite modified impedimetric biosensor to detect Fetuin-A in real blood samples

Uygun, Zihni Onur; Şahin, Çağdaş; Yılmaz, Merve; Akçay, Yasemin; Akdemir, Ali; Sağın, Ferhan Girgin

doi:10.1016/j.ab.2017.11.007

Cited by 31 publications

(22 citation statements)

References 25 publications

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“…Therefore, EIS was carried out in 50 mM pH=7.0 PBS, which includes 100 mM KCl and 5 mM Fe(CN) 6 3−/4− redox couples . Its parameters were set as 10.000–0.05 Hz frequency, 180 mV AC and 10 mV DC potentials . The modification processes was carried outby using platinum screen‐printed electrodes(PtE).…”

Section: Methodsmentioning

confidence: 99%

A Novel Chronoimpedimetric Glucose Sensor in Real Blood Samples Modified by Glucose‐imprinted Pyrrole‐Aminophenylboronic Acid Modified Screen Printed Electrode

Uygun

2019

Electroanalysis

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In this study, a molecularly imprinted sensor technology is engineered to detect glucose in real blood samples by chronoimpedimetrically. The imprinting process of glucose (Glc) was carried out by electrochemical polymerization of aminophenylboronic acid (APBA) and pyrrole (Py) by performing cyclic voltammetry (CV). Afterwards, glucose molecule was removed from imprinted surface by 5 % acetic acid to reveal glucose imprinted cavities. Electrochemical Impedance Spectroscopy (EIS) was used to characterize sensor modification steps and glucose removal. Glucose monitoring process was carried out chronoimpedimetrically(CI) for the first time in real blood samples. Calibration curve was prepared between 20–800 mg/dL. The standard deviations of the 18 calibration curves R2 were calculated as 0.9866±0.0066 to assess reproducibility. Recovery was calculated by using 105 mg/dL Glc Serum Sample, which was monitored by auto analyzer and into this sample 50 mg/dL Glc added and our sensor response was 147.92±2.43 mg/dL, 98.6±1.62 % (n=5). Non‐imprinted (NIP) sensor gave no signal for the glucose concentration.

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Section: Methodsmentioning

confidence: 99%

A Novel Chronoimpedimetric Glucose Sensor in Real Blood Samples Modified by Glucose‐imprinted Pyrrole‐Aminophenylboronic Acid Modified Screen Printed Electrode

Uygun

2019

Electroanalysis

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“…There are numerous studies on the development of C 60 -based immunosensors in the medical diagnosis of various disorders that occur because of any deterioration in our body's metabolism [2]. Recently, some studies have been carried out with real samples, and the capability of C 60 -modified immunosensors has been demonstrated in the determination of microorganisms [142][143][144]. Additionally, the use of fullerene in immunosensors has been reported to facilitate the electron transfer between the redox proteins and the electrode [145].…”

Section: Immunosensors Based On Functionalized Fullerenementioning

confidence: 99%

Nano-carbons in biosensor applications: an overview of carbon nanotubes (CNTs) and fullerenes (C60)

2020

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Recently, the use of carbon nanotubes (CNTs) and fullerenes in the design of new biosensors have attracted great interest in the development of carbon nanomaterials. Due to the superior properties of CNTs and fullerenes, the use of sensor components allows the development of reliable, accurate and fast biosensors. Depending on the types of target molecules, the development and application areas of the sensors vary. This review summarizes the role of CNTs and fullerenes in the development of biosensors in different application areas. Considering the difference between other members of the nano-carbon family, we explain why CNTs are used more widely in biosensor applications and why fullerenes have high potentials in these areas of application. Moreover, we focused on investigating the function of these nano-carbons in the detection of various analytes in bio-sensing. By discussing the challenges and future expectations, we have put forward a perspective that may help synthesize advanced composites in the development of new generation designs in biosensor applications.

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“…According to the authors, the designed biosensor has great potential to detect ATP at ultralow levels (detection limit of 3.30 fM). Recent works have shown the design of sensors for L-histidine [32], prostate antigen [151], proteins [152,153], biomarkers [154,155], and several others biomolecules [156][157][158][159].…”

Section: Great Response Formentioning

confidence: 99%

Carbon Nanostructure-based Sensors: A Brief Review on Recent Advances

Bezzon

Montanheiro

Menezes

et al. 2019

Advances in Materials Science and Engineering

116

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A brief review reporting the recent advances on the carbon nanostructured materials-based sensors covering recently published works is presented. Several works dealing with experimental and theoretical data are reviewed and discussed. The main results for carbon nanotubes, nanodiamonds, fullerene, graphene, and hybrid carbon-nanostructured devices that show sensing properties in different fields were considered for the discussions. The goal of this paper was to highlight sensor mechanisms, and the best results reached up to now are creating bases for further applications.

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Fullerene-PAMAM(G5) composite modified impedimetric biosensor to detect Fetuin-A in real blood samples

Cited by 31 publications

References 25 publications

A Novel Chronoimpedimetric Glucose Sensor in Real Blood Samples Modified by Glucose‐imprinted Pyrrole‐Aminophenylboronic Acid Modified Screen Printed Electrode

A Novel Chronoimpedimetric Glucose Sensor in Real Blood Samples Modified by Glucose‐imprinted Pyrrole‐Aminophenylboronic Acid Modified Screen Printed Electrode

Nano-carbons in biosensor applications: an overview of carbon nanotubes (CNTs) and fullerenes (C60)

Carbon Nanostructure-based Sensors: A Brief Review on Recent Advances

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