Fullerene C60 modified gold electrode and nanogold modified indium tin oxide electrode for prednisolone determination

Goyal, Rajendra N.; Oyama, Munetaka; Bachheti, Neeta; Singh, Sudhanshu P.

doi:10.1016/j.bioelechem.2008.10.001

Cited by 32 publications

(14 citation statements)

References 20 publications

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“…From the obtained results and previous report [31] am echanism for the electrochemical reduction of prednisolone was confirmed and presented in Scheme 1.…”

Section: Influence Of the Scan Rate On The Prednisolone Peak Current supporting

confidence: 81%

“…Numerous studies have been presented withd ifferent prednisolone determination methods including spectroscopy [17],s pectrophotometry [18,19],g as chromatography [20][21][22],c hemiluminescence [23] and high performance liquid chromatography (HPLC) coupled with various detector [24][25][26][27].H owever these methods generate lots of chemical wastesa nd also require time consuming sample preparation connected with risk of its contamination.S uch inconveniences can be eliminated using electrochemical methods,w hich provide high sensitivity,l ow limit detectiona nd simple procedure of sample preparation.C lassical polarography [28,29] and different voltammetry techniques were used for prednisolone determination.R ecently,t wo voltammetric methodsw ere developed for the analyte determinationi nd rug samples based on oxidation of prednisolone at glassy carbon electrode [30] and at fullerene-C60-modified gold electrode [ 31], with detectionl imits respectively 4.5·10 À7 mol L À1 and 2.6 ·10 À5 mol L…”

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confidence: 99%

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A Novel Method of High Sensitive Determination of Prednisolone on Renewable Mercury Film Silver Based Electrode

2015

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[a] 1IntroductionGlucocorticoids are group of important medications with wide variety of use,m ainly due to their anti-inflammatory and immunosuppressive properties.H uman body produces natural corticoids which are necessaryf or propers ecretion of other hormones and keeping homeostasis. However, affecting the balance of adrenalh ormones excretion may cause diseases connected with necessity of using their synthetic analogs in very little and controlled doses.T aking drugs containingc orticoids is connected with the risk of serious adversee ffects,t hus quality control of medications consisting this group of active substances shouldb ev ery precise [1,2].Prednisolone ((11b)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione [8].P rednisolone derivative is also used in ophthalmologya sacontent of eye drops used to reducea llergic reactionsa ffecting eyes, such as swellinga nd itching [ 9,10].D ue to its immunosuppressive properties is also widely use after organ transplantation [11] and as ah ormone substitution for patients unable to produce proper amounts of corticosteroids on its own [12].L ong term usage of this corticoid may cause serious side effectsl ike gaining weight, high blood pressure,m usclew eakness,o steoporosis,h igh glucose level in body fluids or mentalh ealth problems [13][14][15][16].Numerous studies have been presented withd ifferent prednisolone determination methods including spectroscopy [17],s pectrophotometry [18,19],g as chromatography [20][21][22],c hemiluminescence [23] and high performance liquid chromatography (HPLC) coupled with various detector [24][25][26][27].H owever these methods generate lots of chemical wastesa nd also require time consuming sample preparation connected with risk of its contamination.S uch inconveniences can be eliminated using electrochemical methods,w hich provide high sensitivity,l ow limit detectiona nd simple procedure of sample preparation.C lassical polarography [28,29] and different voltammetry techniques were used for prednisolone determination.R ecently,t wo voltammetric methodsw ere developed for the analyte determinationi nd rug samples based on oxidation of prednisolone at glassy carbon electrode [30] . One of the methodso fa chieving high sensitivity in voltammetry is development in the working electrode constructionf ield. Va rious typeso fm etal film electrodes were constructed recently.A mongt hem lead, gallium and mercury were most frequently used [35][36][37].I nteresting solution of renewable mercury film electrode was proposed by Baś and Kowalski[ 38].W ith the renewable Abstract:F ast and sensitive method of prednisoloned eterminationa tr enewable mercury film electrodeu sing differentialp ulse adsorptive stripping voltammetry (DPAdSV) was successfully developed. Thee ffects of various factors such as:p reconcentration potential and time, pulse height, step potential and supporting electrolyte composition were optimized.Alinear voltammetric response for analyte was obtained in the concentration), with ad etectionl imit of 0.01 mmolL À1 ...

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“…From the obtained results and previous report [31] am echanism for the electrochemical reduction of prednisolone was confirmed and presented in Scheme 1.…”

Section: Influence Of the Scan Rate On The Prednisolone Peak Current supporting

confidence: 81%

mentioning

confidence: 99%

A Novel Method of High Sensitive Determination of Prednisolone on Renewable Mercury Film Silver Based Electrode

2015

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“…This would be a noticeable difference from the electrode modification of other carbon materials, such as fullerenes 64,65 and carbon nanotubes. [66][67][68] However, the variety of techniques available also suggests that there is no established method for electrode surface modification at present.…”

Section: Characteristic Features In the Preparations Of Mnp-rgo 5·1 Rmentioning

confidence: 97%

Recent Nanoarchitectures in Metal Nanoparticle-Graphene Nanocomposite Modified Electrodes for Electroanalysis

Oyama

Chen

2014

ANAL. SCI.

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While increasing attention has been devoted to the use of carbon-based nanomaterials or metal nanoparticles (MNPs) as electrode modifiers for electroanalysis, there is a noticeable development in studies using MNP-graphene nanocomposites or nanohybrids in very recent years. In this review, first, very recent nanoarchitectures in MNP-graphene nanocomposites for modifying electrodes (mainly in 2013) are summarized together with the targets and achievements of electroanalysis. The variety of nanoarchitectures comes from the fact that graphene oxide and metal precursor ions can be reduced chemically or electrochemically, and concurrently or stepwisely. By browsing various preparation methods of the modified electrodes, some characteristic and interesting features of the preparations of MNP-graphene nanocomposites are described together with the possibilities and prospects as electrode modifiers for electroanalysis.

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“…The oxidation of prednisolone which is very rare was reported on the surface of C 60 -Au modified GCE (at + 0.5 V vs. Ag/AgCl) [28].…”

Section: Electrooxidation Behavior Of Prednisolonementioning

confidence: 98%

“…Electrochemical sensors have attracted increasing attention because of their many advantages, such as low detection limit, low cost, rapid response and mainly convenient miniaturization. In this way, several electrochemical methods have proved to be sensitive and reliable for the determination of prednisolone in the presence of other glucocorticoid compounds [24][25][26][27][28].…”

Section: Introductionmentioning

confidence: 99%

Nanoscale Manipulation of Prednisolone as Electroactive Configuration Using Molecularly Imprinted‐Multiwalled Carbon Nanotube Paste Electrode

Rezaei

Mirahmadi-Zare

2011

Electroanalysis

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Prednisolone has no suitable configuration for electroactivation in the potential window from À1.2 to + 1.5 V. In this paper, a new catalytic application of molecularly imprinted polymers (MIP) was employed to achieve a suitable prednisolone conformation for electrochemical oxidation. Also, MIP as a recognition element improved the selectivity of the sensor for determination of prednisolone. In addition, to improve the sensitivity of the electrode multiwalled carbon nanotubes (MWCNT) were used in the preparation of MIP. Using differential pulse voltammetry (DPV) under optimized conditions, the calibration curve showed a linear dynamic range (0.08-160.00 mM) with a detection limit of 0.05 mM (S/N = 3). The modified electrode was successfully applied as prednisolone sensor in real samples such as plasma, urine and pharmaceutical formulation.

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Fullerene C60 modified gold electrode and nanogold modified indium tin oxide electrode for prednisolone determination

Cited by 32 publications

References 20 publications

A Novel Method of High Sensitive Determination of Prednisolone on Renewable Mercury Film Silver Based Electrode

A Novel Method of High Sensitive Determination of Prednisolone on Renewable Mercury Film Silver Based Electrode

Recent Nanoarchitectures in Metal Nanoparticle-Graphene Nanocomposite Modified Electrodes for Electroanalysis

Nanoscale Manipulation of Prednisolone as Electroactive Configuration Using Molecularly Imprinted‐Multiwalled Carbon Nanotube Paste Electrode

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