Frozen section diagnosis of pancreatic malignancy: A sensitive diagnostic technique

Intraoperative consultation in digestive surgery. A consecutive series of 800 frozen sections

“…Published studies in the literature have mostly concerned frozen section consultation for patients operated in very different types of surgical units [22][23][24][25][26][27][28][29]. Several studies have specifically evaluated the value of frozen section analysis in esophagogastric [4], hepatobiliary [5][6][7][8][9][10][11][12][13] or pancreatic [14][15][16][17][18][19][20][21] surgery.…”

“…Cioc et al found a 1.4% discordant diagnosis rate in 284 frozen section analyses of pancreatic lesions or resection margins [17]. This rate was 2% in the series of Doucas et al concerning 310 pancreatic biopsies [16], and 19% in the series of Campanale et al [14] concerning 251 pancreatic biopsies. Couvelard et al found a 6% rate of discordant results in 188 frozen section analyses on pancreatic resection margins in patients undergoing operation for intraductal papillary mucinous tumors [20].…”

Les examens extemporanés en chirurgie digestive. À propos d’une série consécutive de 800 examens

“…Les travaux publiés dans la littérature sont habituellement menés sur des examens extemporanés de malades opérés dans des services de chirurgie variés [22][23][24][25][26][27][28][29]. Certaines études ont toutefois déjà évalué plus spécifiquement l'intérêt de l'examen extemporané en chirurgie oesogastrique [4], hépa-tobiliaire [5][6][7][8][9][10][11][12][13] ou pancréatique [14][15][16][17][18][19][20][21].…”

Lessons Learned From Mistakes and Deferrals in the Frozen Section Diagnosis of Bronchioloalveolar Carcinoma and Well-Differentiated Pulmonary Adenocarcinoma

“…1,2 Pathologists are generally trained to avoid making false-positive diagnoses of malignancy and tend to defer the diagnoses of difficult lesions. 3 This practice can help avoid unnecessary major procedures, but false-negative and deferred diagnoses also result in second surgeries, increasing morbidity and cost of care.…”